|
|
|
| Analysis on the medication rules of replenishing qi and nourishing yin method in treating heart palpitation and chest bi by Professor Mao Dexi |
| ZHAO Chuang1 LU Yongping2 |
1.The Second Clinical Medical College, He’nan University of Chinese Medicine, He’nan Province, Zhengzhou 450002, China;
2.Department of Functional Examination, He’nan Provincial Hospital of Traditional Chinese Medicine, He’nan Province, Zhengzhou 450002, China |
|
|
|
Abstract Objective To explore the medication rules of replenishing qi and nourishing yin method in treating heart palpitation and chest bi by Professor Mao Dexi. Methods The outpatient medical records of replenishing qi and nourishing yin method in treating heart palpitation and chest bi by Professor Mao Dexi in Hall of Famous Doctor of He’nan Provincial Hospital of Traditional Chinese Medicine from February 2018 to January 2020 were collected, which were input into traditional Chinese medicine inheritance assist platform (V2.5). The frequency analysis, association rules and complex entropy cluster analysis were used to analyze the medication rules of Professor Mao Dexi in the treatment of heart palpitation and chest bi. Results A total of 67 prescriptions were enrolled, including 28 heart palpitation prescriptions and 39 chest bi prescriptions. The commonly used drugs for heart palpitation were Radix Ophiopogonis, Radix Pseudostellariae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae and Radix Salviae Miltiorrhizae, and 13 commonly used couplet medicines and 4 new prescriptions were excavated. The commonly used drugs for chest bi were Radix Ophiopogonis, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Radix Astragali seu Hedysari, Radix Pseudostellariae, Radix Paeoniae Rubra, and 14 commonly used couplet medicines and 4 new prescriptions were excavated. Conclusion Through data mining technology, it is found that Professor Mao Dexi often uses modified Shengmai Powder to treat heart palpitation and chest bi with syndrome of deficiency of both qi and yin. For patients with heart palpitation due to malnutrition of heart blood, the drugs of invigorating spleen and calming heart, nourishing blood for tranquillization, such as Semen Ziziphi Spinosae, Poria, Radix Angelicae Sinensis, and Radix Rehmanniae Recens, and others were used. For patients with excess syndrome, the drugs of promoting blood circulation for removing blood stasis, clearing heat and promoting diuresis, such as Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, and others were added. For patients with chest bi, Ramulus Cinnamomi and Bulbus Allii Macrostemonis were used for warming heart yang, Fructus Trichosanthis and Fructus Aurantii Immaturus were used for relieving chest stiffness and resolving masses, Rhizoma Ligustici Chuanxiong and Radix Salviae Miltiorrhizae were used for promoting blood circulation for removing blood stasis.
|
|
|
|
|
|
[1] 陈伟伟，高润霖，刘力生，等.中国心血管病报告2016概要[J].中国循环杂志，2017，32（6）：521-530.
[2] 严亚锋，白海侠，董斌.基于挖掘的国医大师张学文治疗胸痹用药规律研究[J].辽宁中医杂志，2018，45（6）：1179-1182.
[3] 于林童，曲文白，余新波，等.数据挖掘方法在名老中医用药规律研究中的应用现状[J].中医杂志，2017，58（10）：886-888，900.
[4] 唐仕欢，申丹，卢朋，等.中医传承辅助平台应用评述[J].中华中医药杂志，2015，30（2）：329-331.
[5] 封继宏，张鹏宇.数据挖掘在现代中医药研究中的应用进展[J].中国医药导报，2020，17（13）：54-57.
[6] 郑昆，吴嘉瑞，张非非.基于数据挖掘的中医治疗冠心病用药规律研究[J].中国医药导报，2017，14（36）：113-116.
[7] 王永炎，鲁兆麟.中医内科学[M].2版.北京：人民卫生出版社，2011.
[8] 国家药典委员会.中华人民共和国药典[M].北京：中国医药科技出版社，2015.
[9] 钟赣生.中药学[M].北京：中国中医药出版社，2012.
[10] 杨洪军，唐仕欢，卢朋.中医传承辅助平台的开发与应用[M].福州：福建科学技术出版社，2013：45.
[11] 陈子茵，陈腾宇，陈国铭，等.基于数据挖掘的国医大师治疗心悸用药规律探讨[J].中国中医基础医学杂志，2020， 26（1）：58-61.
[12] 谢宛君，林毅，钟少文，等.基于数据挖掘的林毅教授治疗肉芽肿性乳腺炎用药规律探析[J].中国医药导报，2019， 16（3）：120-123.
[13] 曲文白，于林童，邹思畅，等.廖家桢教授应用气血理论治疗冠心病心绞痛血瘀证的临床数据挖掘研究[J].中国中西医结合杂志，2020，40（7）：868-871.
[14] 包海兰，李玲玲，徐伟，等.基于《中医方剂大辞典》的银屑病外用方剂用药规律数据挖掘[J].中医杂志，2019， 60（11）：974-978.
[15] 牛嫚嫚.朱翠玲教授治疗冠心病稳定型心绞痛合并抑郁症组方用药规律研究[D].郑州：河南中医药大学，2018.
[16] 孙卉丽，刘玉霞，王亚红，等.基于数据挖掘的郭维琴教授治疗冠心病用药规律分析[J].中华中医药学刊，2015， 33（3）：624-626.
[17] 綦向军，陈国铭，陈腾宇，等.基于数据挖掘国医大师治疗胸痹心痛的用药规律分析[J].中国中医基础医学杂志，2019，25（12）：1685-1688，1692.
[18] 索红亮，曾垂义，毛德西.毛德西教授诊治心血管病“三味”方简析[J].时珍国医国药，2015，26（4）：989-990.
[19] 索红亮，曾垂义.毛德西治心血管病三味方[N].中国中医药报，2013-11-27（005）.
[20] 庄逸洋，黄楚栓，李荣，等.基于数据挖掘的陈镜合治疗心悸用药规律研究[J].中国中医基础医学杂志，2017， 23（10）：1402-1404，1432.
[21] 岳磊，朱丹妮，严永清，等.生脉散复方化学动态变化与药效关系研究——生脉散中五味子化学动态变化（Ⅶ）[J].中国中药杂志，2006，31（12）：1010-1012.
[22] 曾垂义，毛德西.毛德西辨治冠心病经验[J].中国中医基础医学杂志，2017，23（10）：1408-1409.
[23] 苏有玲.基于数据挖掘的许杰治疗冠心病用药经验[J].国医论坛，2019，34（5）：50-53.
[24] 毛德西.冠心病的整体辨证思维[J].中医学报，2010，25（6）：1107-1108.
[25] 石若玉.毛德西教授辨治胸痹验案举隅[J].中医研究，2019，32（12）：34-36. |
|
|
|
