非药物干预措施对晚期肿瘤患者癌性疼痛控制及睡眠质量的影响

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Abstract Objective To explore the application effect of non-pharmaceutical interventions in the control of cancer pain in patients with advanced cancer. Methods From July 2017 to June 2019, a total of 92 patients with advanced tumors admitted to Huai’an First Hospital Affiliated to Nanjing Medical University were selected and divided into 48 cases in the experimental group and 44 cases in the control group by random number table method. The control group was given analgesic care based on the principle of three steps of cancer pain relief, and the experimental group was combined with non-drug interventions on the basis of the control group. Followed up for three months, the visual analogue scale (VAS), pittsburgh sleep quality index (PSQI), and the general quality of life scale for cancer patients (FACT-G) were used to assess the degree of pain, sleep quality, and quality of life. Results After three months of follow-up, the VAS scores of the two groups were decreased significantly, and the differences were statistically significant (P ＜ 0.05). The VAS score of the experimental group was lower than that of the control group, and the difference was statistically significant (P ＜ 0.05). The incidence of moderate and severe pain in the two groups were decreased significantly, and the differences were statistically significant (P ＜ 0.05). The incidence of moderate and severe pain in the experimental group were lower than those in the control group, and the differences were statistically significant (P ＜ 0.05 or P ＜ 0.01). The PSQI scores and total scores of the two groups were significantly lower than those before the intervention, and the differences were statistically significant (P ＜ 0.05); the sleep quality, time to fall asleep, sleep time, sleep efficiency, sleep disturbance, daytime function and PSQI total scores of the experimental group were lower than those of the control group, and the differences were statistically significant (P ＜ 0.05). There was no statistically significant difference in the hypnotic drug scores between the two groups (P ＞ 0.05). The FACT-G scores and total scores of the two groups were significantly higher than those before the intervention, and the differences were highly statistically significant (P ＜ 0.01). The physiological status, functional status, emotional status, social and family status and FACT-G total score of the experimental group were higher than those of the control group, and the differences were highly statistically significant (P ＜ 0.01). Conclusion Non-pharmaceutical intervention can help relieve cancer pain in patients with advanced tumors, and improve sleep quality and quality of life.

Key words： Advanced cancer Cancer pain Non-pharmacological managements Sleep quality Quality of life

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	WU Mengyuan1 WANG Xiaoyan2▲ XIE Ruhui1

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WU Mengyuan1 WANG Xiaoyan2▲ XIE Ruhui1. Effects of non-pharmaceutical interventions on cancer pain control and sleep quality in patients with advanced tumors[J]. 中国医药导报, 2021, 18(10): 167-171.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I10/167

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