针刺联合椎管内镇痛在分娩镇痛中安全及有效性的meta分析

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Abstract Objective To systematically evaluate the safety and efficacy of acupuncture combined with intraspinal analgesia in labor analgesia. Methods The databases of PubMed, Embase, Cochrane Library, CNKI, Wanfang Data, CBM and VIP were searched by computer, and the randomized controlled trials of acupuncture combined with intraspinal labor analgesia were collected. The retrieval time was from the inception to August 2020. The literatures that met the criteria were screened and meta-analysis was carried out by RevMan 5.3. Results Ten literatures were included, including 872 patients. The results of meta-analysis showed that the conversion rate of vaginal delivery to cesarean section (OR = 0.45, 95%CI [0.26, 0.77], P = 0.003), postpartum hemorrhage volume (MD = -45.14, 95%CI [-85.32, -4.96], P = 0.03) and intraspinal drug dosage (MD = -4.35, 95%CI [-5.97, -2.74], P ＜ 0.000 01) in the experimental group were lower than those in the control group. However, there was no significant differences between the two groups in visual analogue scales of cervix with full open (MD = -0.19, 95%CI [-0.45, 0.07], P = 0.15) and the time of active phase of the first stage of labor (MD = -15.79, 95%CI [-32.83, 1.24], P = 0.07). Conclusion Compared with intraspinal labor analgesia, acupuncture combined with intraspinal analgesia can reduce the intraspinal drug dosage and postpartum hemorrhage volume, and reduce the rate of vaginal delivery to cesarean section. However, it still needs to be verified by large sample, multi-center and high quality studies.

Key words： Acupuncture Delivery Analgesia Meta-analysis Randomized controlled trial

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	SHUI Linhui1 HE Huixin1 PENG Sai1 DENG Chaowen1 TENG Yongjie1 LEI Huajuan1 LI Zikui2

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SHUI Linhui1 HE Huixin1 PENG Sai1 DENG Chaowen1 TENG Yongjie1 LEI Huajuan1 LI Zikui2. Meta-analysis on the safety and efficacy of acupuncture combined with intraspinal analgesia in labor analgesia[J]. 中国医药导报, 2021, 18(10): 108-112.

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https://www.yiyaodaobao.com.cn/EN/ OR https://www.yiyaodaobao.com.cn/EN/Y2021/V18/I10/108

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