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| Analysis on the medication rule of invigorating the spleen medical school in the treatment of emotional diseases based on data mining |
| LI Yunxi1 LIN Waner1 YANG Lingling2 ZHENG Liming2 LI Yan2 |
1.The Second Clinical Medical College, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510405, China;
2.Department of Psychology and Sleep, Guangdong Provincial Hospital of Chinese Medicine, Guangdong Province, Guangzhou 510405, China |
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Abstract Objective To explore the medication rules of invigorating the spleen medical school in the treatment of emotional diseases. Methods The database of medication for emotional diseases was established with the works of the representative doctors of invigorating the spleen as the data source, and the factor analysis and systematic cluster analysis were carried out on the included prescriptions and Chinese medicine. Results A total of 126 prescriptions were included, involving 156 Chinese herbs. The drug use frequency was 1100 times. The top 5 frequently used herbs were Ginseng Radix et Rhizoma, Angelicae Sinensis Radix, Glycyrrhizae Radix et Rhizoma Praeparata Cum Melle, Glycyrrhizae Radix et Rhizoma, Bupleuri Radix. The most frequently used efficacy of included herbs was tonifying deficiency, relieving superficies, and clearing heat. The four nature of drugs mainly included warm and cold. The five flavors mainly included pungent, sweet, and bitter. The channel tropism of Chinese herbs mainly included spleen, lung, heart, and stomach. Nine common factors were extracted from the factor analysis, the cumulative variance contribution rate was 68.007%, and the high-frequency herbs were classified into 6 categories in the systematic cluster analysis. Conclusion The principle of treatment of invigorating the spleen medical school for emotional diseases is treating deficiency syndrome with strengthening primordial qi of spleen and stomach method, treating excess syndrome with purging fire method. At the same time, they pay attention to the ascending and dredging of yang qi of spleen and stomach. While syndrome of intermingled deficiency and excess should combine the three principles of treatment, which are invigorating spleen and stomach, clearing yin-fire, ascending yang qi.
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