|
|
|
| Anti adhesion effects of absorbable medical membrane in stage two cholecystectomy |
| FAN Zhongbao1 SHEN Jianfen2 LIU Qingfeng1▲ LIAN Hao1 |
1.The First Department of General Surgery, People’s Hospital of China Medical University People’s Hospital of Liaoning Province, Liaoning Province, Shenyang 110001, China;
2.Cardiovascular Medicine Department, the First Affiliated Hospital of China Medical University, Liaoning Province, Shenyang 110001, China |
|
|
|
Abstract Objective To observe the efficacy of Dikang absorbable medical membrane in preventing adhesion during stage two cholecystectomy. Methods One hundred and twenty patients with cholecystolithiasis and cholecystitis admitted to People’s Hospital of China Medical University from January 2017 to January 2019 were selected and divided into control group and observation group according to random number table method, 60 cases in each group. Control group was treated with laparoscopic cholecystolithotomy and cholecystostomy; on the basis of control group, observation group covered the gallbladder surface and gallbladder triangle with Dikang absorbable medical membrane. The second stage operation situation, the second stage operation adhesion, the first stage postoperative follow-up one, two, three months operation area pain of two groups were compared. Results The operation time of observation group was shorter than that of control group, the intraoperative blood loss of observation group was less than that of control group, and the conversion rate of observation group was lower than that of control group, the differences were statistically significant (P < 0.05). The degree of adhesion in observation group was significantly lighter than that in control group, the difference was statistically significant (P < 0.05). The incidence rate of postoperative pain and visual simulation score in observation group were lower than those in control group at one, two, three months after operation, and the differences were statistically significant (P < 0.05). Conclusion Dikang absorbable medical membrane can effectively prevent local tissue adhesion after surgery.
|
|
|
|
|
|
[1] 曾凡刚，郭怀斌，李凤飞，等.胆囊三角粘连成因及对腹腔镜胆囊切除术影响的研究进展[J].中国医师杂志，2019， 21（6）：958-960.
[2] Torres-De La Roche LA，Campo R，Devassy R，et al. Adhesions and anti-adhesion systems highlights [J]. Facts Views Vis Obgyn，2019，11（2）：137-149.
[3] Guhan S，Peng SL，Janbatian H，et al. Surgical adhesives in ophthalmology：history and current trends [J]. Br J Ophthalmol，2018，102（10）：1328-1335.
[4] Negahi AR，Hosseinpour P，Vaziri M，et al. Comparison of honey versus polylactide anti-adhesion barrier on peritoneal adhesion and healing of colon anastomosis in rabbits [J]. Open Access Maced J Med Sci，2019，7（10）：1597-1601.
[5] 欧妙娴，蒋亚玲，黄晓珍.中重度宫腔粘连分离术后不同方法预防再粘连的比较[J].实用医学杂志，2019，29（23）：2704-2708.
[6] Kojima Y，Sakamoto K，Tomiki Y，et al. Experience in the use of a device to attach an anti-adhesion-absorption barrier film to the abdominal cavity in laparoscopic colorectal surgery [J]. J Minim Access Surg，2020，16（4）：449-450.
[7] 陈孝平，汪建平.外科学[M].9版.北京：人民卫生出版社，2019.
[8] 吴硕东.胆石病的诊断与治疗[M].北京：人民卫生出版社，2018.
[9] 林海燕，冯湘利，韩毓，等.异位妊娠腹腔镜手术40例术后应用防粘连的治疗及IL-10、CRP水平分析[J].湖南师范大学学报：医学版，2019，16（6）：138-140.
[10] 李衍飞，杜前程，张蒙召，等.保胆取石术适应证及术后结石复发预防措施的再认识[J].临床肝胆病杂志，2019， 35（3）：690-695.
[11] 史甲平.腹腔镜胆囊切除术中转开腹的并发症及影响因素[J].临床医学研究与实践，2018，3（23）：57-58.
[12] Sharma P，Aguilar R，Nader MA，et al. Weekend effect in acute pancreatitis-related hospital admissions in the united states：an analysis of the nationwide inpatient sample [J]. Pancreas，2018，47（4）：418-424.
[13] 金海敏，黄海，李晓文，等.胆囊并发胆总管结石患者的微创外科治疗研究[J].中国内镜杂志，2018，24（7）：62-66.
[14] Lee HS，Chung MJ，Park JY，et al. Urgent endoscopic retrograde cholangiopancreatography is not superior to early ERCP in acutebiliary pancreatitis with biliary obstruction without cholangitis [J]. PLoS One，2018，13（2）：e0190835.
[15] Zubia-Olaskoaga F，Maraví-Poma E，Urreta-Barallobre I，et al. Development and validation of a multivariate prediction model for patients with acute pancreatitis in intensive care medicine [J]. Pancreatology，2018，18（2）：161-167.
[16] 杨澎，朱宇.保胆取石术治疗胆囊结石203例回顾性研究[J].肝胆胰外科杂志，2018，30（1）：58-61.
[17] 吴涛.腹腔镜胆囊切除术与微创保胆取石术治疗胆囊结石的近远期疗效对比分析[J].赣南医学院学报，2019， 39（2）：150-152，170.
[18] 宫斌.微创保胆取石术对胆结石患者术后胆囊壁厚度及胆囊功能水平的影响[J].实用医技杂志，2018，25（7）：769-770.
[19] 金义.腹腔镜联合胆道镜胆囊切除术治疗胆囊结石患者的临床疗效[J].当代医学，2018，24（4）：68-69.
[20] D’Amore L，Ceci F，Mattia S，et al. Adhesion prevention in ventral hernia repair：an experimental study comparing three lightweight porous meshes recommended for intraperitoneal use [J]. Hernia，2017，21（1）：115-123.
[21] Seyam E，Ibrahim EM，Youseff AM，et al. Laparoscopic management of adhesions developed after peritoneal nonclosure in primary cesarean section delivery [J]. Obstet Gynecol Int，2018，2018：6901764.
[22] 陈灶妹，李茹冰.可吸收防粘连膜的应用研究与未来展望[J].中国组织工程研究，2017，21（18）：2920-2926.
[23] 吴馥凌，侯楚祺，夏秋香，等.术后腹腔粘连中西医防治方法研究与应用[J].中国药业，2019，28（20）：1-4.
[24] 徐锋，彭灿，张尚文.可吸收医用膜在腹部外科手术中预防术后肠粘连的临床调查观察[J].中外医学研究，2016， 14（7）：155-157.
[25] 杜晓龙，宋涛，欧学海，等.医用可吸收膜在腕管综合征切开松解术中应用的疗效评价[J].美中国际创伤杂志，2019，18（1）：33-35. |
|
|
|
