自体月经血来源干细胞治疗宫腔粘连的研究进展

Abstract
Figure/Table
References (31)
Related Citation (15)

Download: PDF (570 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract The intrauterine adhesions are a kind of common endometrial injury diseases. In addition, the occurrence of intrauterine adhesions is related to the decrease of endometrial stem cells and functional defects, so stem cell transplantation provides a new possibility for the treatment of intrauterine adhesions. Therefore, how to treat intrauterine adhesions, prevent the recurrence of adhesions, and solve the pregnancy needs of patients is one of the urgent clinical problems. Among them, menstrual blood stem cells have been widely studied for their advantages such as rapid proliferation, multiple sampling, non-trauma, and no ethical issues and so on. This article reviews the prospect of autologous menstrual blood stem cells in the treatment of intrauterine adhesions in recent years, and provides a new idea for the treatment of intrauterine adhesions.

Key words： Menstrual blood stem cells Endometrium Intrauterine adhesions Infertility

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	MA Hailan1 LIU Mengting2 WANG Wei1▲

Cite this article:

MA Hailan1 LIU Mengting2 WANG Wei1▲. Research progress of autologous menstrual blood derived stem cells in the treatment of intrauterine adhesions[J]. 中国医药导报, 2021, 18(8): 46-49.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2021/V18/I8/46

[1] Asherman JG. Amenorrhoea traumatica（atretica）[J]. J Obstet Gynaecol Emp，1948，55（1）：23-30.
[2] 张红红，李文.宫腔粘连的治疗策略及进展[J].中华生殖与避孕杂志，2018，38（3）：238-251.
[3] 吴华颖，卢美松，邓锁.宫腔粘连的发生机制及诊治现状[J].中国计划生育和妇产科，2018，10（10）：15-17.
[4] 黄燕花.宫腔粘连诊疗研究进展[J].医学理论与实践，2018，31（10）：1437-1439.
[5] Gilman AR，Dewar KM，Rhone SA，et al. Intrauterine adhesions following miscarriage：look and learn [J]. J Obstet Gynaecol Can，2016，38（5）：453-457.
[6] Hooker AB，Lemmers M，Thurkow AL，et al. Systematic review and meta-analysis of intrauterine adhesions after miscarriage：prevalence，risk factors and long-term reproductive outcom [J]. Hum Reprod Update，2014，20（2）：262-278.
[7] 黄晓梅.人工流产致宫腔粘连的研究[J].中外医疗，2018， 37（9）：196-198.
[8] Hooker A，Fraenk D，Br?觟lmann H，et al. Prevalence of intrauterine adhesions after termination of pregnancy：a systematic review [J]. Eur J Contracept Reprod Health Care，2016，21（4）：329-335.
[9] Yu X，Yuhan L，Dongmei S，et al. The incidence of post-operative adhesion following transection of uterine septum： a cohort study comparing three different adjuvant therapies [J]. Eur J Obstet Gynecol Reprod Biol，2016， 201：61-64.
[10] 邵翠芳，谢秀英.宫腔粘连相关细胞因子的研究进展[J].中国生育健康杂志，2018，29（1）：89-91.
[11] Chan RW，Schwab KE，Gargett CE. Clonogenicity of human endometrial epithelial and stromal cells [J]. Biol Reprod，2004，70（6）：1738-1750.
[12] Meng X，Ichim TE，Zhong J，et al. Endometrial regenerative cells：a novel stem cell population [J]. J Transl Med，2007，5：57.
[13] 李杨杨，张佳佳，何荣霞.子宫内膜再生与干细胞移植治疗宫腔粘连研究进展[J].医学研究生学报，2018，52（4）：95-99.
[14] 郑圣霞，刘雨生.月经血源性子宫内膜干细胞移植治疗重度宫腔粘连的临床前期研究[D].合肥：安徽医科大学，2015.
[15] 吴琳，申东翔，张慧蓉，等.脂肪干细胞在宫腔粘连中的应用进展及前景[J].实用医学杂志，2019，35（3）：496-499.
[16] 池余刚，胡丽娜.宫腔粘连术后辅助治疗的研究进展[J].现代妇产科进展，2019，28（2）：77-79.
[17] Mou XZ，Lin J，Chen JY，et al. Menstrual blood-derived mesenchymal stem cells differentiate into functional hepatocyte-like cells [J]. J Zhejiang Univ Sci B，2013，14（11）：961-972.
[18] Alawadhi F，Du H，Cakmak H，et al. Bone marrow-derived stem cell（BMDSC）transplantation improves fertility in a murine model of Asherman’s syndrome [J]. PLoS One，2014，9（5）：e96662.
[19] 张娟.人工流产致宫腔粘连的研究进展[J].医药前沿，2019，9（20）：9-10.
[20] Kilic S，Yuksel B，Pinarli F，et al. Effect of stem cell application on Asherman syndrome，an experimental rat model [J]. J Assist Reprod Genet，2014，31（8）：975-982.
[21] Zhang Y，Lin X，Dai Y，et al. Endometrial stem cells repair injured endometrium and induce angiogenesis via AKT and ERK pathways [J]. Reproduction，2016，152（5）：389-402.
[22] 王中洁，冯明月，邓艳阳.宫腔粘连治疗及预防复发的临床研究进展[J].吉林医学，2019，40（2）：366-368.
[23] Nagori CB，Panchal SY，Patel H. Endometrial regeneration using autologous adult stem cells followed by conception by in vitro fertilization in a patient of severe Asherman’s syndrome [J]. J Hum Reprod Sci，2011，4（1）：43-48.
[24] Singh N，Mohantly S，Seth T，et al. Autologous stem cell transplantation in refractory Asherman’s syndrome-A novel cell based therapy [J]. J Hum Reprod Sci，2014，7（2）：93-98.
[25] Santamaria X，Cabanillas S，Cervelló I，et al. Autologous cell therapy with CD133+ bone marrow-derived stem cells for refractory Asherman’s syndrome and endometrial atrophy：a pilot cohort study [J]. Hum Reprod. 2016， 31（5）：1087-1096.
[26] Tan J，Li P，Wang Q，et al. Autologous menstrual blood-derived stromal cells transplantation for severe Asherman’s syndrome [J]. Hum Reprod，2016，31（12）：2723-2729.
[27] Ma H，Liu M，Li Y，et al. Intrauterine transplantation of autologous menstrual blood stem cells increases endometrial thickness and pregnancy potential in patients with refractory intrauterine adhesion [J]. J Obstet Gynaecol Res，2020，46（11）：2347-2355.
[28] Aghajanova L，Hoffman J，Mok-Lin E，et al. Obstetrics and Gynecology Residency and Fertility Needs [J]. Reprod Sci，2017，24（3）：428-434.
[29] 关艳杰.中重度宫腔粘连病因及治疗研究进展[J].陕西医学杂志，2020，49（2）：254-256.
[30] 何文，孙晓溪.子宫内膜干细胞治疗宫腔粘连的研究进展[J].中华生殖与避孕杂志，2020，40（11）：E038.
[31] 潘嘉佳，郑小冬，沈晓露，等.经皮雌激素治疗中重度宫腔粘连术后的疗效观察[J].现代实用医学，2020，32（5）：42-43，80.