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| Analysis of knowledge graph of endoplasmic reticulum stress research based on VOSviewer and CiteSpace |
| YANG Yige HUI Yuanhui▲ ZHANG Guanghui XU Rongrong XUE Wenjing CHAI Ruoning |
| Department of Cardiology, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China |
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Abstract Objective To analyze the research status, classic literature, hot spots and frontiers of endoplasmic reticulum stress in the past 10 years. Methods The literature on endoplasmic reticulum stress included in the Web of Science database were retrieved from January 2010 to September 2020, while VOSviewer and CiteSpace Ⅴ software were used to study the number of publications, literature citations, keywords, keyword burst detection and time zone diagram for visual analysis. Results A total of 22 021 SCI articles were included. The amount of publications was increasing year by year. The articles of David et al. were cited the most. The research hotspots were focused on autophagy and apoptosis, oxidative stress, unfolded protein, etc. Conclusion This article reveals the research strength, development context, research hotspots and frontiers of this field in the past 10 years, and provides references for future scholars’ research.
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