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The value of CT Bhalla score in evaluating the prognosis of patients with bronchiectasis |
ZHOU Jie1 WEN Ting2 GAO Wei2 |
1.Department of Radiology, Suqian Hospital Affiliated to Xuzhou Medical University Suqian People’s Hospital of Nanjing Drum-Tower Hospital Group, Jiangsu Province, Suqian 223800, China;
2.Department Pneumology, Suqian Hospital Affiliated to Xuzhou Medical University Suqian People’s Hospital of Nanjing Drum-Tower Hospital Group, Jiangsu Province, Suqian 223800, China |
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Abstract Objective To explore the estimated value of the prognosis of patients with bronchiectasis by CT Bhalla score. Methods A total of 80 patients with bronchiectasis admitted to Suqian People’s Hospital of Nanjing Drum-Tower Hospital Group from January 2016 to December 2018 were included. After admission, all patients received CT Bhalla score. Clinical data of the patients were collected, including gender, age, body mass index, risk grade, smoking history, duration of disease, number of acute exacerbations, Pseudomonas aeruginosa positiveness, percentage of forced expiratory volume in the first second to the predicted value (FEV1%pred), and the relationship between CT Bhalla score and clinical characteristics of the patients was analyzed. The patients were followed up for 12 months to analyze the prognosis, and were divided into good group (16 cases) and bad group (64 cases) according to the conditions of prognosis. CT Bhalla score was compared between the two groups, and receiver operating characteristic curve (ROC) was drawn to analyze the predictive value of CT Bhalla score in the prognosis of patients with bronchiectasis. Results CT Bhalla scores ranged from five to seventeen, with an average score of (9.27±1.26). There were statistically significant differences in CT Bhalla scores among patients with different ages, risk grade, duration of disease, number of acute exacerbations, Pseudomonas aeruginosa positiveness and FEV1%pred (all P < 0.05). Among them, the CT Bhalla scores of high risk patients were significantly higher than those of medium risk patients and low risk patients, and medium risk patients were higher than those of low risk patients, and patients with acute exacerbations ≥three times per year were significantly higher than those with acute exacerbations two times per year and those with acute exacerbations one time per year. Patients with acute exacerbations two time sper year were significantly higher than those with acute exacerbations one time per year, with statistically significant differences (all P < 0.05). CT Bhalla score in the bad group was significantly higher than those in the good group, and the difference was highly statistically significant (P < 0.01). The AUC of CT Bhalla score for poor prognosis was 0.731 (standard error = 0.065, 95%CI = 0.603-0.859, P = 0.002), the best cutoff was 9.490 scofres, the sensitivity was 72.70%, and the specificity was 65.90%. Conclusion CT Bhalla score has a certain predictive value for the prognosis of patients with bronchiectasis.
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