原发性高血压患者无创血流动力学参数与心脏结构变化的相关性分析

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Abstract Objective To study the correlation between non-invasive hemodynamic parameters and cardiac structure changes in patients with essential hypertension. Methods A total of 300 patients with essential hypertension who were followed up at Wuzhou Traditional Chinese Medicine Hospital in Guangxi Zhuang Autonomous Region from June 2017 to June 2019 were selected as the research group, and a total of 100 healthy people who received outpatient physical examination during the same period were selected as the control group. The differences in general clinical data, non-invasive hemodynamic parameters and cardiac structural changes between the two groups were compared, and the correlation between non-invasive hemodynamic parameters and cardiac structural changes related parameters was analyzed. Results There were no statistically significant differences between the two groups in age, gender, history of smoking, drinking, diabetes, coronary heart disease, low-density lipoprotein and creatinine (P ＞ 0.05). The left atrium diameter, left ventricular end diastolic diameter, left ventricular end systolic diameter, left ventricular posterior wall thickness, ventricular septal thickness and left ventricular mass index in the study group were significantly higher than those in the control group, and the differences were statistically significant (P ＜ 0.05); the left ventricular ejection fraction was lower than that of the control group, and the difference was statistically significant (P ＜ 0.05). The peripheral vascular resistance and peripheral vascular resistance index of the study group were significantly higher than those of the control group, and the differences were statistically significant (P ＜ 0.05); the stroke volume, stroke index, cardiac output, heart index and left heart work index of the study group were significantly lower than those of the control group, and the differences were statistically significant (P ＜ 0.05). Peripheral vascular resistance and peripheral vascular resistance index were positively correlated with left ventricular end-systolic inner diameter, left ventricular posterior wall thickness, and left atrial inner diameter (r ＞ 0, P ＜ 0.05); while they were negatively correlated with left ventricular ejection fraction, stroke volume, stroke index and cardiac output and cardiac index (r ＜ 0, P ＜ 0.05). Conclusion The non-invasive hemodynamic parameters of patients with essential hypertension have a good correlation with the related parameters of the heart structure, which can be used as a reference index for evaluating changes in the heart structure.

Key words： Essential hypertension Noninvasive hemodynamic parameters Cardiac structure Correlation

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	WANG Zhanxian LUO Hongmin JIANG Xingjuan

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WANG Zhanxian LUO Hongmin JIANG Xingjuan. Correlation analysis of non-invasive hemodynamic parameters and cardiac structure changes in patients with essential hypertensions[J]. 中国医药导报, 2021, 18(5): 53-56,60.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2021/V18/I5/53

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