|
|
Clinical application of CT value and IC value of spectral CT scan in qualitative assessment of lymph nodes in gastric adenocarcinoma |
LI Zuyin ZHU Di XIA Chunhua▲ |
Department of Radiology, the First People’s Hospital of Hefei, Anhui Province, Hefei 230061, China |
|
|
Abstract Objective To explore the application value of CT value and iodine concentration (IC) value in the arterial and venous phase in the spectral CT scan in the qualitative assessment of the lymph nodes in gastric adenocarcinoma. Methods A total of 85 patients with gastric adenocarcinoma admitted to the First People’s Hospital of Hefei, from February 2016 to July 2020 were selected as the research objects. All patients underwent conventional CT scan and spectral CT scan. The CT values and IC values of the arterial and venous phases of metastatic lymph nodes and non-metastatic lymph nodes were compared, and the CT values and IC values of the arterial and venous phases of metastatic lymph nodes of different degrees of differentiation were compared. The receiver operating characteristic (ROC) curve of the quantitative parameters of spectral CT in the differential diagnosis of gastric adenocarcinoma lymph node metastasis was drawed, and its diagnostic efficiency was analyzed. Results The CT values and IC values of arterial and venous phase of metastatic lymph nodes were significantly higher than those of non-metastatic lymph nodes, the differences were statistically significant (all P < 0.05). In metastatic lymph nodes, the CT values and IC values of arterial and venous phase of poorly differentiated adenocarcinoma were significantly lower than those of moderately and highly differentiated adenocarcinoma, the differences were statistically significant (all P < 0.05). The area under the curve (AUC) of the arterial phase CT value, venous phase CT value, arterial phase IC value, and venous phase IC value in the diagnosis of gastric adenocarcinoma lymph node metastasis are 0.803, 0.712, 0.849 and 0.784, respectively, they had high accuracy in judging lymph node metastasis of gastric adenocarcinoma. Conclusion The CT value and IC value of arterial and venous phase in spectral CT scan have important value in preoperative evaluation of lymph node properties of patients with gastric adenocarcinoma, which can be used as quantitative indicators to evaluate the condition, efficacy and prognosis of patients with gastric adenocarcinoma.
|
|
|
|
|
[1] 王鑫毅,徐锦媚,白雪莲,等.CT能谱成像对胃癌诊断价值的初步探讨[J].现代肿瘤医学,2020,28(13):2295-2299.
[2] 王睿,李靖,方梦捷,等.基于能谱CT的影像组学术前预测进展期胃癌淋巴结转移的价值[J].中华医学杂志,2020,100(21):1617-1622.
[3] 陈小华,李佳音,李莉明,等.感兴趣区选择对胃癌能谱CT测量结果可重复性的影响及与微血管密度的关系[J].中华放射学杂志,2018,52(1):24-29.
[4] Li R,Li J,Wang X,et al. Detection of gastric cancer and its histological type based on iodine concentration in spectral CT [J]. Cancer Imaging,2018,18(1):42.
[5] 史志勇.能谱CT定量分析在非小细胞肺癌术前诊断中的临床价值[J].中国CT和MRI杂志,2020,18(9):76-78,177.
[6] Rengo M,Dharampal A,Lubbers M,et al. Impact of iodine concentration and iodine delivery rate on contrast enhancement in coronary CT angiography:a randomized multicenter trial(CT-CON)[J]. Eur Radiol,2019,29(11):6109-6118.
[7] 陈琼英,赵雪峰,韩福刚.胃癌能谱CT表现与肿瘤标志物CEA、CYFRA21-1浓度的相关性[J].中国老年学杂志,2019,39(13):3148-3151.
[8] 陈丽红,薛蕴菁,段青,等.不同病理类型和分化程度胃癌宝石CT能谱曲线及CT值的比较[J].中华肿瘤杂志,2019,41(5):363-367.
[9] 王夏婉,高剑波,柴亚如.CT能谱成像在胃腺癌分化程度评估中的应用价值[J].放射学实践,2017,32(4):410-413.
[10] Cheng SM,Ling W,Zhu J,et al. Dual Energy Spectral CT Imaging in the assessment of Gastric Cancer and cell proliferation:A Preliminary Study [J]. Sci Rep,2018,8(1):17619.
[11] 周岩,王云,杨晓晔,等.能谱CT用于胃癌术前肿瘤浸润深度和淋巴结转移的诊断价值研究[J].现代消化及介入诊疗,2019,24(12):1481-1484.
[12] 甘郑宁,马梦雪,严小娟.能谱CT成像碘物质定量分析在肝细胞癌鉴别诊断中的应用价值[J].肝脏,2020, 25(7):695-698.
[13] 王芋霖,向守洪,李宁,等.能谱CT定量参数对肺磨玻璃结节定性诊断的价值[J].肿瘤,2020,40(7):488-495.
[14] Perisinakis K,Tzedakis A,Spanakis K,et al. The effect of iodine uptake on radiation dose absorbed by patient tissues in contrast enhanced CT imaging:Implications for CT dosimetry [J]. Eur Radiol,2018,28(1):151-158.
[15] 欧玲,邵平,李兮力,等.宝石能谱CT多参数成像对脂肪肝定量测定的临床价值[J].中国CT和MRI杂志,2020, 18(10):90-92.
[16] 范艳芬,郁义星,胡梦洁,等.CT预测原发性肝细胞癌微血管侵犯研究进展[J].临床放射学杂志,2020,39(6):1225-1228.
[17] 王宁,刘兆玉.能谱探测器CT在提高下肢动脉血管成像质量中的应用[J].中国临床医学影像杂志,2020,31(8):600-603.
[18] 杜江华,韩秉艳,宋娟,等.双源CT标准化碘浓度及能谱曲线在胃癌周围侵犯诊断中的应用价值[J].医学影像学杂志,2018,28(3):426-430.
[19] 陈丽芳,傅钢泽,黄定品,等.能谱CT容积碘含量在晚期胃癌化疗疗效评价中的价值[J].中华胃肠外科杂志,2019(10):977-983.
[20] 张益兰,史讯,许凤.能谱CT淋巴结短长径比和动脉期碘基值联合诊断胃癌淋巴结转移性的价值[J].重庆医学,2018,47(32):4156-4159.
[21] Zhou Z,Liu Y,Meng K,et al. Application of spectral CT imaging in evaluating lymph node metastasis in patients with gastric cancers:initial findings [J]. Acta Radiol,2019, 60(4):415-424.
[22] 吕悦,刘爱连,刘静红,等.能谱单能量图像影像组学在胃癌分级中的应用[J].中国医学计算机成像杂志,2018, 24(5):421-425.
[23] 柴亚如,高剑波,邢静静,等.能谱CT定量参数对胃癌淋巴结的定性评估价值[J].中华胃肠外科杂志,2017, 20(3):309-314.
[24] 欧阳华忠,尹红军,贾文霄,等.CT能谱成像在胃癌周围侵犯评价中的应用研究[J].中国CT和MRI杂志,2018, 16(7):129-132.
[25] 吉玉刚,陈光强,范国华,等,吴旭东.双源CT能谱参数对Lauren弥漫型与肠型胃癌的鉴别诊断价值[J].放射学实践,2020,35(9):1122-1126. |
|
|
|