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| Progress in the diagnosis of sepsis in children |
| LIN Xiaofei1 GU Xiaohai1 YU Chunlin1 ZHU Hongli1 WU Yunduo1 ZHANG Jun1 WANG Yumei2 |
1.Department of Pediatrics, the Huai’an Maternity and Child Clinical College of Xuzhou Medical University, Jiangsu Province, Huai’an 223002, China;
2.Neonatal Disease Screening Center, the Huai’an Maternity and Child Clinical College of Xuzhou Medical University, Jiangsu Province, Huai’an 223002, China |
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Abstract The early diagnosis and treatment of sepsis has always been the focus of pediatric critical illness. In recent years, the World Health Organization (WHO) bring forth the concept of “integrated intervention of prevention, diagnosis and clinical treatment”. A group of authoritative experts in the field of emergency treatment in China have also taken the lead in projecting the “prevention of sepsis campaign in China” (PSCC), but how to effectively coordinate and deal with relevant issues in clinical work, especially how to make early accurate diagnosis and take bundle strategy of intensive treatment for the later stage is still a hot issue that needs active attention. In this paper, some new reaearch and related progress of the diagnostic methods of children sepsis, such as biomarkers, multi-dimensional scoring methods, physiological parameters and variables of diagnostic significance, and the prediction system of mechanical sepsis are reviewed in order to provide reference for early diagnosis and accurate treatment of children sepsis in the future, and to offer assistance for clinicians.
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