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| Exploration study on traditional Chinese medicine syndrome of patients after transcatheter aortic valve replacement |
| YU Zikai1 WU Yongjian2▲ CHEN Keji1▲ |
1.Cardiovascular Center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China;
2.Coronary Heart Disease Center, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China |
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Abstract Objective To explore the distribution of traditional Chinese medicine syndromes in patients after transcatheter aortic valve replacement (TAVR). Methods Seventy elderly patients with severe aortic stenosis who were successfully treated with TAVR in Fuwai Hospital, Chinese Academy of Medical Sciences from January 2018 to January 2019 were selected. The symptoms and physicochemical indexes of patients were gathered, and the main syndromes were concluded according to the clinical data by using cluster analysis. Results The top ten traditional Chinese medicine syndromes symptoms of patients after TAVR were tiredness and weakness (88.6%), shortness of breath after exercise (77.4%), palpitation after exercise (77.1%), dry mouth (70.0%), spiritlessness and lazy speech (60.0%), white and greasy fur (57.1%), stabbing pain in chest and hypochondrium (55.7%), palpitation and oppression in chest (54.3%), sweating after activity (52.9%), dark red tongue (52.9%). The results of cluster analysis showed that traditional Chinese medicine syndromes can be summarized as yang deficiency syndrome, syndrome of deficiency of both qi and yin, qi and blood deficiency, blood stasis and water stagnation syndrome. Conclusion Traditional Chinese medicine syndromes of patients after TAVR operation are mainly yang deficiency syndrome, qi and yin deficiency syndrome, qi and blood deficiency, blood stasis and water stagnation syndrome. It provides a theoretical basis for the treatment of traditional Chinese medicine
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