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| Effect of Polylactic Acid Gel combined with artificial cycle therapy after hysteroscopy transcervical resection of adhesion |
| XIA Zhiyong LAN Li RAN Wei |
| Department of Obstetrics and Gynecology, Affiliated Hospital of North Sichuan Medical College, Sichuan Province, Nanchong 637000, China |
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Abstract Objective To study the application effect of Polylactic Acid Gel combined with artificial cycle therapy after hysteroscopic transcervical resection of adhesion(TCRA). Methods A total of 210 patients with intrauterine adhesions (IUA) who underwent TCRA in Affiliated Hospital of North Sichuan Medical College from December 2018 to February 2020 were retrospectively analyzed, according to treatment methods, they were divided into experimental group (108 cases) and control group (102 cases). Control group was treated with artificial cycle therapy after TCRA, and experimental group was treated with Polylactic Acid Gel on the basis of control group. After three cycles of treatment, the uterine cavity morphology, menstrual improvement and incidence of readhesion, uterine cavity volume and endometrial thickness, and adverse reactions were compared between two groups. Results The total effective rates of uterine cavity morphology and menstruation improvement in experimental group were higher than those in control group, with statistically significant (P ＜ 0.05). The incidence of readhesion in experimental group was lower than that in control group, with statistically significant (P ＜ 0.05). Uterine cavity volume in experimental group was bigger than that in control group and endometrial thickness in experimental group was higher than that in control group, with statistically significant (P ＜ 0.05). There was no significant difference in the total incidence of adverse reactions between two groups (P ＞ 0.05). Conclusion The efficacy of Polylactic Acid Gel combined with artificial cycle therapy after hysteroscopic TCRA is significant, which is worthy of application and promotion.
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