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| Analysis of risk factors affecting middle-aged and elderly type 2 diabetes patients with DR |
| AN Yan GAO Jianqin GUO Caihong ZHU Wei |
| Department of Endocrinology, Beijing Aerospace General Hospital, Beijing 100076, China |
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Abstract Objective To explore the risk factors that affect middle-aged and elderly type 2 diabetes patients with diabetic retinopathy (DR), and to provide a basis for the prevention of such complications in the clinic. Methods A total of 171 middle-aged and elderly patients diagnosed with type 2 diabetes and relatively complete data records from the Department of Endocrinology, Beijing Aerospace General Hospital from January to December 2018, were divided into DR group (56 cases) and control group (115 cases) according to whether they occurred DR. The age, body mass index (BMI), course of diabetes, triacylglycerol (TG), total cholesterol (TCHO), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), fasting blood glucose (FPG), glycosylated hemoglobin (HbA1c), blood uric acid (UA), urine microalbumin/creatinine (UMA) levels of two groups were collected to analyze. Results There were no significant difference in BMI, LDL-C and HDL-C between the two groups (P ＞ 0.05). The course of disease in the DR group was longer than that in the control group, while TG, TCHO, FPG, HbA1c, UA and UMA were higher than those in the control group, and the differences were statistically significant (P ＜ 0.05). Logistic multivariate regression analysis showed that the course of diabetes (OR = 1.27, 95%CI: 1.11-1.45, P ＜ 0.05), TG (OR = 2.06, 95%CI: 1.30-3.25, P ＜ 0.05), HbA1c (OR = 2.92, 95%CI: 1.79-4.76, P ＜ 0.05) and UMA (OR = 1.00, 95%CI: 1.00-1.01, P ＜ 0.05) were independent risk factors for DR. Conclusion In middle-aged and elderly patients with type 2 diabetes, the course of diabetes, TG, HbA1c, and UMA are risk factors for DR.
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