不同手术时机治疗高血压脑出血的临床效果对比

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Abstract Objective To compare the clinical effect of treatment for hypertensive cerebral hemorrhage at different operation opportunities. Methods The clinical data of 95 cases of patients with hypertensive cerebral hemorrhage admitted to Department of Neurosurgery, Weinan Central Hospital from May 2013 to May 2016 was analyzed retrospectively. All patients were treated with intracranial hematoma puncture drainage and they were divided into three groups according to different operation time: ultra-early group (24 cases), the time from bleeding to surgery was ＜6 h; early group (39 cases), the time from bleeding to surgery was 6-12 h; late group (32 cases), the time from bleeding to surgery was ＞12 h. The incidence of rehaemorrhagia after operation for 72 h and the conditions of prognosis and quality of life after operation for 1 year in the three groups were compared. Results The incidence of rehaemorrhagia after operation in early group (15.4%) was lower than that of ultra-early group (58.3%) and late group (56.3%), the differences were statistically significant (P ＜ 0.05). Followed up for one year after operation, the grading of Glasgow outcome score (GOS) in early group was significantly better than that of ultra-early group and late group (P ＜ 0.05); the scores of World Health Organization quality of life questionnaire (WHOQOL-BREF) in the three groups were all higher than those before operation (P ＜ 0.05), and the score of WHOQOL-BREF in early group was significantly higher than that of ultra-early group and late group, the differences were statistically significant (P ＜ 0.05). Conclusion For patients with hypertensive cerebral hemorrhage, the operation within 6-12 h after bleeding can obviously decrease the incidence of rehaemorrhagia, improve the quality of life, which has good clinical application value.

Key words： Hypertensive cerebral hemorrhage Drainage of intracranial hematoma Operation opportunity Quality of life

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	DUAN Jiqiang1 YAO Sheng1 WANG Yang1 WANG Feng1 SUI Long2

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DUAN Jiqiang1 YAO Sheng1 WANG Yang1 WANG Feng1 SUI Long2. Comparison on the clinical effect of treatment for hypertensive cerebral hemorrhage at different operation opportunities[J]. 中国医药导报, 2018, 15(2): 71-74.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I2/71

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