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Experience of self-made Huayu Tongluo Decoction in the treatment of diabetic foot based on collateral disease theory |
BA Yuanming1,2* HU Jinqing3,4* XIE Yonghua3,4 LI Lingli3,4 GU Ruixin3,4 WANG Yun3,4 |
1.Department of Nephrology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province, Wuhan 430061, China;
2.Hubei Institute of Traditional Chinese Medicine, Hubei Province, Wuhan 430074, China;
3.Department of Traditional Chinese Medicine, the Fourth Hospital of Wuhan City, Hubei Province, Wuhan 430032, China;
4.Pu’ai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province, Wuhan 430032, China |
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Abstract Diabetic foot is one of the common chronic complications of diabetes mellitus. It is located in the veins of the limbs. It has the characteristics of severe disease, rapid development, high disability and mortality rate. It belongs to the category of “collateral disease-vascular system disease”. The pathological basis and basic pathogenesis of diabetic foot is deficiency of qi and yin and the syndrome of intermingled phlegm and blood stasis, which cause heat-toxicity and necrotic pathogen blocking collaterals. The method of removing blood stasis and unblocking collaterals based on the principle of “using collaterals for circulation” is widely used in the treatment of diabetic foot. In clinical practice, the effect of self-made Huayu Tongluo Decoction on diabetic foot is significant, which can significantly improve the clinical symptoms of patients, and the drug is simple, safe, and treated with both manifestion and root cause, which is worthy of clinical promotion. This article introduces the experience of treating diabetic foot with self-made Huayu Tongluo Decoction.
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[1] Gudala K,Bansal D,Muthyala H,et al. Prevalence and risk factors of diabetic peripheral neuropathy in type 2 diabetes mellitus outpatients [J]. Value Health,2013,16(3):A173.
[2] Apelqvist J,Bakker K,van Houtum WH,et al. International consensus and practical guidelines on Group on the Diabetic Foot [J]. Diabetes Metab Res Rev,2000,16(Suppl 1):S84-S92.
[3] Olokoba AB,Obateru OA,Olokoba LB. Type 2 diabetes mellitus:a review of current trends [J]. Oman Med J,2012, 27(4):269-273.
[4] Shomali M. Diabetes treatment in 2025:can scientific advances keep pace with prevalence? [J]. Ther Adv Endocrinol Metab,2012,3(5):163-173.
[5] Ajala O,English P,Pinkney J. Systematic review and meta-analysis of different dietary approaches to the management of type 2 diabetes [J]. Am J Clin Nutr,2013,97(3):505-516.
[6] Green MF,Aliabadi Z,Green BT. Diabetic foot:evaluation and management [J]. South Med J,2002,95(1):95-101.
[7] Kajagar BM,Godhi AS,Pandit A,et al. Efficacy of low level laser therapy on wound healing in patients with chronic diabetic foot ulcers-a randomised control trial [J]. Indian J Surg,2012,74(5):359-363.
[8] Lee KM,Kim WH,Lee JH,et al. Risk factors of treatment failure in diabetic foot ulcer patients [J]. Arch Plast Surg,2013,40(2):123-128.
[9] 陈育群,周一农,刘加和,等.应用湿性愈合换药方法治疗4例糖尿病足的体会[J].中国现代医生,2014,52(16): 149-152.
[10] 吴海霞.刺五加注射液治疗糖尿病足溃疡的临床观察[J].中国中西医结合杂志,2003,23(4):299.
[11] 王丽翔,张磊,闫少庆,等.解毒通脉散联合煨脓长肉膏治疗糖尿病足溃疡24例临床观察[J].中医杂志,2011, 52(15):1283-1285.
[12] 黄英志.叶天士医学全书[M].北京:中国中医药出版社,1999:591.
[13] 胡锦庆,巴元明,丁霑,等.基于络病理论探讨糖尿病足溃疡的中医病机及治疗[J].辽宁中医杂志,2017,44(1):51-53.
[14] 李萍,杨丽彩,盛巡,等.络病学在疮疡病理生理及诊疗中的应用[J].中医杂志,2002,43(4):308-312.
[15] 朱建新,朱芳红.从络病学说论治糖尿病足的体会[J].中医临床研究,2011,3(20):73-74.
[16] 黎敏姬,潘卓文,张绍芬,等.四妙勇安汤加减对糖尿病足的临床疗效观察[J].内蒙古中医药,2016,5(10):10.
[17] 周甜,胡泰然,胡家才,等.加味四妙勇安汤治疗糖尿病足下肢溃疡疗效观察[J].微循环学杂志,2016,26(3):46-53.
[18] 秦永山.中西医结合治疗糖尿病足48例[J].中西医结合中国民间疗法,2010,18(12):47-48.
[19] 崔炎,吴建萍,李晓绿,等.四妙勇安汤对糖尿病足坏疽患者 VEC、ET和致炎细胞因子水平的影响[J].河南中医,2009,29(2):151-152.
[20] 黄学锋,张秋玲.四妙勇安汤加味治疗糖尿病足临床疗效观察[J].中医药学报,2009,37(5):89-90.
[21] 王光宁,李伟东,蔡宝昌.四妙勇安汤不同提取部位抗炎作用的研究[J].广东药学院学报,2009,25(4):389-391.
[22] 黄金玮,常柏.四妙勇安汤对2型糖尿病大鼠血管内皮细胞功能的影响[J].天津中医药,2010,27(6):499-500.
[23] 许颖智,张军平,李明.四妙勇安汤对动脉粥样硬化斑块易损指数的影响及机制探讨[J].中华中医药杂志,2010, 25(12):2298-2301.
[24] 张军平,许颖智,李明.四妙勇安汤对动脉粥样硬化模型兔氧化应激及炎症反应的影响[J].中医杂志,2010, 51(1):72-74.
[25] 刘晓颖,李凤文.水蛭对实验性动脉粥样硬化家兔血管内皮功能障碍的影响[J].中国中医基础医学杂志,1998, 4(3):16-18,66.
[26] 李兆星,陈钰妍,李顺详.地龙的研究概况[J].湖南中医药杂志,2011,13(11):444-446.
[27] 白凤瑞,吕志阳.药用地龙的研究进展[J].黑龙江中医药,2010,23(14):610-613.
[28] 崔春淼,付慕勇.生肌膏对糖尿病足患者的疗效及其创面愈合相关指标及预后的影响分析研究[J].中国中西医结合外科杂志,2020,26(1):58-61.
[29] 胡锦庆,巴元明,姜楠,等.高频彩超观察天楼解毒消肿散质量糖尿病足疗效[J].中华中医药杂志,2018,33(6):2669-2671.
[30] 李旗,田福玲,张文丽,等.消毒愈肌膏对糖尿病足患者创面肉芽组织VEGF/SDF-1α/CXCR4蛋白表达的影响[J].中国中西医结合杂志,2017,37(2):165-168. |
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