老年抑郁症患者体重降低的影响因素分析

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Abstract Objective To observe the weight loss of elderly depression patients, and to explore the factors influencing weight loss in elderly depression patients, so as to guide future weight intervention for elderly depression patients. Methods One hundred and ten elderly depression patients treated in Department of Gerontology, Mental Health Center, Shanghai Jiaotong University School of Medicine from January 2018 to December 2019 were prospectively selected. According to article 16 of HAMD-24 version, the weight loss was assessed and divided into weight loss group (weight loss of at least 0.5 kg within one week) and no weight loss group, and a self-made general information questionnaire was used to collect patient data. The influencing factors of weight loss in elderly patients with depression were analyzed by single-factor and multi-factor analysis. Results Among 110 elderly patients with depression, 46 cases lost weight, with an incidence of 41.82%. After a single logistic regression analysis and a multiple regression model were established, the results of multivariate analysis showed that anxiety-type depression, diabetes, high level of CRP, high level of IL-6 were the influencing factors of weight loss in elderly depression patients (OR = 11.528, 9.135, 5.141, 2.809, P < 0.05). Conclusion The incidence of weight loss in elderly patients with depression is high, which may be affected by factors such as anxiety-type depression, diabetes, and high levels of inflammatory factors. The clinic should pay attention to the early intervention of patients with the above risk factors.

Key words： Elderly depression Weight loss Anxiety-type depression Complicated with diabetes mellitus Inflammation

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	HUANG Jingwen WEI Yanyan▲ LIU Yan

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HUANG Jingwen WEI Yanyan▲ LIU Yan. Analysis of influencing factors of weight loss in elderly patients with depression[J]. 中国医药导报, 2021, 18(2): 114-117.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2021/V18/I2/114

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