高需求输血对食管癌切除术后恢复及相关生化指标变化的影响

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Abstract Objective To investigate the causes of high-demand blood transfusion during perioperative period of patients with esophagus cancer, and to analyze the effect of high-demand blood transfusion on postoperative recovery and related biochemical indicators. Methods A stratified cluster sampling method was used to select 58 patients with esophageal cancer admitted to the Department of Thoracic Surgery of the First Hospital of Jiaxing from May 2017 to December 2018, with 29 patients with blood transfusion volume ≥1000 mL during the perioperative period of esophageal cancer resection were divided into the observation group, and 29 patients with blood transfusion volume ＜1000 mL were divided into the control group, the causes and effects of high-demand blood transfusion (blood transfusion volume ≥1000 mL) were analyzed, with the length of stay in the intensive care unit, length of hospital stay, complication rate after esophageal cancer resection, platelet count and blood potassium and calcium levels included. Results The complication rate of the observation group (62.1%) was higher than that of the control group (31.0%), and the difference was statistically significant (P ＜ 0.05). The blood loss during resection of esophageal cancer in the observation group was higher than that in the control group, while the length of stay in the intensive care unit and hospital stay were both longer than those in the control group, and the differences were all statistically significant (all P ＜ 0.05). After blood transfusion, the platelet count of the observation group was lower than that of the control group, and the difference was statistically significant (P ＜ 0.05). After blood transfusion, the blood potassium and calcium levels of the observation group were lower than those of the control group, and the differences were all statistically significant (all P ＜ 0.05). Conclusion The main reason for the high-demand blood transfusion during perioperative period of esophageal cancer resection in patients with esophageal cancer is intraoperative bleeding. High-demand blood transfusion can lead to enhanced postoperative coagulation function and the incidence of complications after esophageal cancer resection will increase.

Key words： High-demand transfusion Esophageal cancer Perioperative period of esophageal cancer resection Anemia

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	CHEN Tao WANG Xuechun GU Xuehong YU Qin

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CHEN Tao WANG Xuechun GU Xuehong YU Qin. Effect of high-demand blood transfusion on postoperative recovery of esophageal cancer and changes in related biochemical indicators[J]. 中国医药导报, 2021, 18(2): 98-101.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2021/V18/I2/98

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