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Analysis of characteristics and pregnancy outcomes in advanced maternal age with heart disease |
ZHAO Junda1 LIANG Lingyun1 YIN Yan2 MA Junqi1 |
1.Department of Gynecology, the First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830054, China;
2.Department of Obstetrics, the First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830054, China |
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Abstract Objective To investigate the characteristics and pregnancy outcomes in advanced maternal age with heart disease. Methods A retrospective analysis was carried out on clinical data of patients with heart disease who delivered in the First Affiliated Hospital of Xinjiang Medical University from January 2008 to December 2017. According to the age, they were divided into 216 cases in the right age group (>18 - <35 years old) and 398 cases in the advanced age group (≥35 years old). The kinds of heart disease and pregnancy outcomes were compared between the two groups. Results The incidence of hypertensive heart disease during pregnancy in the advanced age group was higher than that in the right age group, and the incidence of arrhythmia was lower than that in the right age group, with statistically significant differences (P < 0.05). The incidence of fetal growth restriction and iatrogenic prematurity in the advanced age group were higher than those in the right age group, and the differences were statistically significant (P < 0.05). Conclusion The incidence of advanced maternal age with heart disease was higher than right maternal age. Cardiopathy induced by hypertensive disorders was higher in advanced maternal age, while arrhythmia was higher in right maternal age. Advanced maternal age with heart disease would induce poorer perinatal outcome.
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