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| Progress of the correlation between vitamin D and preeclampsia |
| YUAN Chengkun LU Caixia |
| Department of Obstetrics, the First Affiliated Hospital, Heilongjiang University of Chinese Medicine, Heilongjiang Province, Harbin 150040, China |
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Abstract Preeclampsia as a group of hypertensive disorders during pregnancy, is one of the four leading causes of maternal death. Adequate vitamin D levels play an important role in maternal and child health during pregnancy. Vitamin D is closely associated with the onset of preeclampsia. Its mechanism is mainly related to oxidative stress, immunity, blood pressure regulation and epigenetics. Vitamin D supplementation can reduce the incidence of pregnancy complications, reduce the risk of preeclampsia, and improve adverse pregnancy outcomes. Future high-quality clinical studies are needed to confirm the benefits of vitamin D supplementation for preeclampsia. Vitamin D supplementation may be an effective intervention strategy to prevent preeclampsia.
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