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| Progress in treatment of acute spinal cord injury |
| SHI Yubo YU Ling GUO Weichun |
| Department of Orthopedics, Renmin Hospital of Wuhan University, Hubei Province, Wuhan 430060, China |
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Abstract Acute spinal cord injury results in sensory and motor dysfunction below the level of injury, which seriously affects patients’ quality of life. In recent years, with the deepening studies on pathological mechanism of spinal cord injury, progress has been made in the treatment of acute spinal cord injury. Surgical treatment can rebuild spinal stability and relieve spinal cord compression，resulting in promoting the recovery of neural function, and the timing of surgery should be individualized to patients. Drug therapy plays aneuroprotective role mainly by alleviating secondary injury and promoting nerve regeneration. Cell therapy is the most promising future treatments for acute spinal cord injury; however, how transplanted cell reconstruct the spinal cord structure and function requires further exploration. This article reviews some of the current advances of the treatment in order to provide reference for clinical treatment of acute spinal cord injury.
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