乳腺癌患者分子分型对其创伤后成长水平的影响

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Abstract Objective To explore the impact of molecular classification of breast cancer patients on post-traumatic growth (PTG). Methods This study adopted a cross-sectional survey and used convenience sampling to select 236 breast cancer patients admitted to the First Affiliated Hospital of Bengbu Medical College from January to December 2019 as the research objects. According to molecular classification, they were divided into four groups (Luminal A group, Luminal B group, human epidermal growth factor receptor 2 [HER2] positive group and triple negative group). The post-traumatic growth inventory (PTGI) was used to conduct questionnaire surveys on the four groups of breast cancer patients at the time of puncture diagnosis, one month after diagnosis, three months after diagnosis, and six months after diagnosis, the differences between the groups were compared. Results The average PTG score of breast cancer patients was (51.73±9.02), and there was no statistically significant difference in the total PTG score of the four groups at the time of puncture diagnosis (P ＞ 0.05). The total PTG scores of breast cancer patients in the Luminal B group and HER2 positive group at the time of six months after diagnosis were higher than the total PTG score at the time of diagnosis, and the differences were highly statistically significant (all P ＜ 0.01). At the time of six months after diagnosis, the total PTG score of the Luminal A group was lower than that of the Luminal B group, and the difference was highly statistically significant (P ＜ 0.01). At the time of six months after the diagnosis of breast cancer, the total PTG score of the HER2 positive group was higher than that of the triple negative group, and the difference was statistically significant (P ＜ 0.05). Conclusion The PTG levels of breast cancer patients are at a low-moderate level, and the PTG level of Luminal B and HER2 positive breast cancer patients have changed significantly after a short term. Clinical nursing practice should focus on the PTG of Luminal A and triple negative breast cancer patients.

Key words： Breast cancer Post-traumatic growth level Molecular classification Nursing management

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	ZHANG Xuemei1 WEI Tao1 JIANG Zhaobin1 CHEN Yongxia2 TIAN Wuguo3 YANG Xiumu1▲

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ZHANG Xuemei1 WEI Tao1 JIANG Zhaobin1 CHEN Yongxia2 TIAN Wuguo3 YANG Xiumu1▲. Effect of molecular classification of breast cancer patients on their post-traumatic growth[J]. 中国医药导报, 2020, 17(35): 112-115.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I35/112

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