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| Research progress of RNA binding motif 25 in malignant tumors |
| LI Wanghong TANG Jintian SHU Yin LIU Chen WANG Ruibin WANG Boqing |
| Department of Hepatobiliary and Pancreatic Surgery, Affiliated Cancer Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830011, China |
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Abstract RNA binding motif protein 25 (RBM25) belongs to the RNA-binding protein family. It’s expressed proteins, located in nuclear spots, are shear factors and participate in the selective shearing process of genes. In recent years, more and more scholars have paid attention to the effect of RBM25 on malignant tumors. Current studies have shown that the high and low expression level of RBM25 and abnormal shear have an impact on the occurrence, development, metastasis and prognosis of malignant tumors. This paper reviews the research progress of RBM25 in diverse malignant tumors, such as acute myeloid leukemia, prostate cancer, human papillomavirus positive head and neck malignancies, breast cancer, lung adenocarcinoma, osteosarcoma and colon cancer and so on.
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