耐药非结核分枝杆菌肺部疾病治疗进展

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Abstract Nontuberculous mycobacterial (NTM) infection often causes pulmonary disease, and the most common pathogens are Mycobacterium avium, Mycobacterium abscessus and Mycobacterium kansasii. The therapeutic drugs for different pathogens are different. The identification of bacterial species is the prerequisite for effective treatment. The use of drugs based on guidelines is still the most basic treatment and helps to improve the prognosis, but the development of drug resistance reduces the success rate of treatment. Understanding the mechanism of drug resistance and the characteristics of pathogens can provide targets for the research of new drugs, but there is no new drug that can be applied to clinical patients. Therefore, re-exploring the therapeutic effect of existing drugs can be used as one of the treatment options. This article summarizes the guideline basic drugs for NTM pulmonary disease caused by the above three pathogens and the choice of treatment options after drug resistance.

Key words： Nontuberculous mycobacteria Treatment Drug resistance Human immuno-deficiency virus

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	WEI Huaying YANG Yang WU Yongfeng HUA Wei ZHANG Yulin▲

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WEI Huaying YANG Yang WU Yongfeng HUA Wei ZHANG Yulin▲. Progress in the treatment of drug-resistant nontuberculous mycobacteria in pulmonary disease[J]. 中国医药导报, 2020, 17(34): 52-55.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I34/52

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