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Study on the traditional Chinese medicine treatment and prescription rules of postcholecystectomy syndrome |
ZHANG Wei1 LIU Pengfei1 AN Zhentao1 MA Fumei2 TIAN Yaozhou1 |
1.Department of Gastroenterology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing 210028, China;
2.Department of Internal Medicine, Wuzhong District Traditional Chinese Medicine Hospital of Suzhou City, Jiangsu Province, Suzhou 215107, China |
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Abstract Objective To explore traditional Chinese medicine treatment and prescription rules of postcholecystectomy syndrome (PCS) by data mining. Methods CNKI, Wanfang Data, VIP and PubMed were searched by computer, with the theme of “postcholecystectomy syndrome”, and the retrieval time was from the date of database construction to December 31, 2019. The literatures with TCM treatment were selected for discrimination. After establishing the database, frequency analysis, cluster analysis and association rule analysis were carried out. Results TCM treatment included dispersing stagnated liver qi for promoting bile flow, dispersing liver and regulating qi, clearing heat and eliminating dampness, etc. The prescriptions mainly included Chaihu Shugan Powder, Da Chaihu Decoction, Shugan Lidan Decoction (self-made). Association rules suggested that there were six kinds of commonly used two-drug pairs with support >40% and three kinds of three-drug pairs. Conclusion PCS can be divided into six syndrome types: syndrome of qi stagnation of liver and gallbladder, syndrome of dampness-heat of liver and gallbladder, pattern of static blood obstruction and stagnation, syndrome of stagnation of liver qi and spleen deficiency, syndrome of incoordination between liver and stomach, and spleen-stomach weakness syndrome, which provide references for clinical treatment of TCM.
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