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Analysis of allergic reaction in children with adenoid hypertrophy |
XU Sheng1 CHU Hanqi2 GUAN Hongxia1▲ |
1.Department of Otolaryngology Head and Neck Surgery, Maternal and Child Hospital of Hubei Province, Hubei Province, Wuhan 430070, China;
2.Department of Otolaryngology Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province, Wuhan 430030, China |
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Abstract Objective To analyze the clinical characteristics of allergy indicators (screening of Eosinophils [EOS] and serum allergens) in children with adenoid hypertrophy (AH). Methods A retrospective analysis of 303 inpatients admitted to Department of Otolaryngology at Maternal and Child Health Hospital of Hubei Province from October 2017 to July 2019 with AH as the first diagnosis. According to whether it was accompanied by allergic rhinitis (AR), it was divided into AH group (215 cases) and AH+AR group (88 cases). Peripheral blood was drawn from all children for EOS percentage and serum allergen screening. Results EOS and total IgE in AH+AR group were significantly higher than those in AH group (P < 0.05). The positive rate of allergens in AH+AR group was 29.04%, of which the most common allergens were house dust mite (81.82%), dust mite (68.18%), mold mixture (17.05%) and alternaria alternata (13.64%). The positive rate of a single allergen was 26.14%, and the positive rate of two allergens was 60.23%. There were up to nine types of allergens in the same child. Conclusion Allergic reaction may be one of the pathogenic factors in children with AH. The allergens in children with AH are mainly house dust mites, and the positive degree is more common in mild to moderate.
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