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| The value of saffron in the rehabilitation of sequela of apoplexy |
| WEN Bin KANG Lijuan JIN Lili |
| Department of Emergency, Baoding First Central Hospital, Hebei Province, Baoding 071000, China |
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Abstract Objective To explore the value of saffron in the treatment of rehabilitation of sequela of apoplexy. Methods A total of 120 patients with sequela of apoplexy who were treated at the Baoding First Central Hospital from January 2018 to December 2019 were selected as the research objects. According to the random number table method, they were divided into the conventional group and the saffron group, with 60 cases in each group. The conventional group received routine standardized treatment, and the saffron group added saffron treatment on the basis of the conventional group. After eight weeks of treatment, the treatment effects of the two groups were compared, including the National Institutes of Health Stroke Scale (NIHSS) score, activities of daily living (ADL) score, hemorheological indicators [hematocrit, erythrocyte sedimentation rate, fibrinogen, whole blood viscosity (low cut), whole blood viscosity (high cut), platelet aggregation index] and therapeutic efficacy. Results After treatment, the NIHSS scores of the two groups were significantly lower than before treatment, and the saffron group was significantly lower than that of the conventional group (P ＜ 0.05). After treatment, the ADL scores of the two groups were significantly higher than those before treatment; and the saffron group was significantly higher than that of the conventional group (P ＜ 0.05). After treatment, the hematocrit, erythrocyte sedimentation rate, fibrinogen, whole blood viscosity (low cut), whole blood viscosity (high cut), platelet aggregation index and other hemorheological indicators of the saffron group were significantly lower than those of the conventional group (P ＜ 0.05). Compared with before treatment, the hematocrit, erythrocyte sedimentation rate and fibrinogen of patients in the conventional group were significantly reduced after treatment, and all hemorheological indexes in the saffron group were significantly reduced (P ＜ 0.05). The total effective rate of the saffron group was significantly higher than that of the conventional group (P ＜ 0.05). Conclusion Saffron can significantly improve the neurological function of patients with sequela of apoplexy, can also improve their daily living ability and down-regulate the hemorheology indicators, such as the hematocrit, erythrocyte sedimentation, fibrinogen, whole blood viscosity (low cut）, whole blood viscosity (high cut), platelet aggregation index, to improve the treatment efficiency of patients, which is worthy of clinical promotion.
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