早期直肠癌内镜下黏膜剥离术与经肛门内镜微创手术的临床效果对比

Abstract
Figure/Table
References (20)
Related Citation (15)

Download: PDF (605 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To investigate the efficacy of endoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEM) in the treatment of early colorectal tumors. Methods A total of 211 patients with early rectal cancer (uTis-uT1) who treated in Tangshan People′s Hospital of Hebei Province from May 2010 to May 2016 were selected. They were divided into ESD group (98 cases) and TEM group (113 cases). The operative time, hospital stay, intraoperative bleeding, complete tumor resection, tumor residual and recurrence were compared between the two methods. Postoperative complications such as hemorrhage, perforation, obstruction and stenosis occurred were compared between the two groups. Results The operation time and hospital stay in ESD group were shorter than those in TEM group, and the differences were statistically significants (P < 0.01); and there were no significant differences in intraoperative bleeding, complete tumor resection rate, tumor residual rate and recurrence rate (P ＞ 0.05). There was no statistically significant difference in the incidence of complications between the two groups (P > 0.05). Conclusion Both ESD and TEM are safe and effective in the treatment of early rectal cancer, but the operation time and hospital stay in ESD are significantly shortened.

Key words： Early rectal cancer Endoscopic submucosal dissection Transanal endoscopic microsurgery Treatment

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LI Qingke1 HE Lifang2 LIANG Lei1 HAN Longcai1 MA Guoming1 LIU Yuanting1▲ WANG Zhiwu3

Cite this article:

LI Qingke1 HE Lifang2 LIANG Lei1 HAN Longcai1 MA Guoming1 LIU Yuanting1▲ WANG Zhiwu3. Comparison of clinical effects between endoscopic submucosal dissection and transanal endoscopic microsurgery for early rectal cancer[J]. 中国医药导报, 2020, 17(31): 118-121.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I31/118

[1] Arnold M，Sierra MS，Laversanne M，et al. Global patterns and trends in colorectal cancer incidence and mortality [J]. Gut，2017，66（4）：683-691.
[2] Siegel RL，Miller KD，Jemal A. Cancer statistics，2019 [J]. CA Cancer J Clin，2019，69（1）：7-34.
[3] 张卫刚，张言言，张宪文，等.不同分期结直肠癌患者的预后分析：一项基于SEER数据库的回顾性研究[J].中华结直肠疾病，2017，6（1）：21-27.
[4] 陈万青，郑荣寿，张思维，等.2012年中国恶性肿瘤发病和死亡分析[J].中国肿瘤，2016，25（1）：1-8．
[5] Palacios-Navarro G，Albiol-Pérez S，García-Magari?觡o García I. Effects of sensory cueing in virtual motor rehabilitation. A review [J]. J Biomed Inform，2016，60：49-57.
[6] 申星杰，刘亮，岳鹏，等.老年早期结直肠癌患者内镜下黏膜剥离术安全性疗效及术后整体生活质量调查[J].医学与哲学，2016，37（11）：40-42，59.
[7] Lee D，Lee M，Lee K，et al. Asymmetric Training Using Virtual Reality Reflection Equipment and the Enhancement of Upper Limb Function in Stroke Patients：A Randomized Controlled Trial [J]. J Stroke Cerebrovasc Dis，2014，23（6）：1319-1326.
[8] 高东锋，吕文浩，张林慧，等.内镜与外科手术治疗直肠小神经内分泌肿瘤的回顾性对比研究[J].中华消化内镜杂志，2016，33（7）：447-450.
[9] 王清踪.内镜黏膜下剥离术治疗早期结直肠癌的应用价值[J].中国实用医刊，2016，43（7）：83-84.
[10] 程璞，卢召，黄飞，等.T1期结直肠癌内镜黏膜下剥离术后追加补救腹腔镜根治术的近期疗效分析[J/QL].中国肿瘤：1-5[2020-04-29].http：//kns.cnki.net/kcms/detail/11.2859.R.20200410.1048.014.html.
[11] Kim JB，Lee HS，Lee HJ，et al. Long-Term Outcomes of Endoscopic Versus Surgical Resection of Superficial Submucosal Colorectal Cancer [J]. Dig Dis Sci，2015，60（9）：2785-2792.
[12] McCarty TR，Bazarbashi AN，Hathorn KE，et al. Endoscopic submucosal dissection（ESD）versus transanal endoscopic microsurgery（TEM）for treatment of rectal tumors：a comparative systematic review and meta-analysis [J]. Surg Endosc，2020，34（4）：1688-1695.
[13] Sideris M，Moorhead J，Diaz-Cano S，et al. KRAS Mutant Status，p16 and β-catenin Expression May Predict Local Recurrence in Patients Who Underwent Transanal Endoscopic Microsurgery（TEMS）for Stage I Rectal Cancer [J]. Anticancer Res，2016，36（10）：5315-5324.
[14] Lin G，Qiu HZ. Patient selection and operation standard of transanal endoscopic microsurgery [J]. Zhonghua Wei Chang Wai Ke Za Zhi，2015，18（5）：427-429.
[15] O′Neill CH，Platz J，Moore JS，et al. Transanal Endoscopic Microsurgery for Early Rectal Cancer：A Single-Center Experience [J]. Dis Colon Rectum，2017，60（2）：152-160.
[16] Bloomfield I，Van Dalen R，Lolohea S，et al. Transanal endoscopic microsurgery：a New Zealand experience [J]. 2018，88（6）：592-596.
[17] Leong KJ，Evans J，Davies MM，et al. Transanal endoscopic surgery：past，present and future [J]. Br J Hosp Med（Lond），2016，77（7）：394-402.
[18] 中国抗癌协会大肠癌专业委员会TEM学组.经肛门内镜微创手术（TEM）技术专家共识（2016）[J].消化肿瘤杂志电子版，2016，8（3）：136-138．
[19] Judd S，Nangia S，Levi E，et al. Rectal carcinoid tumor：a delayed localized recurrence 23 years after endoscopic resection [J]. Endoscopy，2014：46 Suppl 1 UCTN：E555-6.
[20] Kim SH，Yang DH，Lee JS，et al. Natural course of an untreated metastatic perirectal lymph node after the endoscopic resection of a rectal neuroendocrine tumor [J]. Intest Res，2015，13（2）：175-179.