肺癌免疫治疗超进展的研究进展

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Abstract In recent years, due to futher understanding of tumor microenvironment, the clinical research of tumor immunotherapy has made great progress, and immunotherapy has become a hot spot in the field of tumor therapy. Since the significant survival advantage of immunocheckpoint inhibitors in non small cell lung cancer patients, immunotherapy is more and more widely used in lung cancer patients, and the special reaction phenomenon after immunotherapy has gradually attracted people′s attention. There are reports showing that the phenomenon of pseudoprogressio and hyperprogressive occurs in some lung cancer patients after immunotherapy. However, there are currently controversies about how to accurately define and distinguish them, and it is challenging to correctly assess this unique tumor response. This article reviews the research on the definition, evaluation criteria, high-risk groups and related predictors of hyperprogression after immunotherapy.

Key words： Lung cancer Immunotherapy Hyperprogression Immune checkpoint inibitors

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	ZHANG Wen SONG Qibin

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ZHANG Wen SONG Qibin. Research progress on hyperprogression of immunotherapy for lung cancer[J]. 中国医药导报, 2020, 17(31): 58-61.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I31/58

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