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| The experience of Professor LU Min in treating diarrhea predominant irritable bowel syndrome |
| KE Shuifang1 LU Min2 |
1.The Third Clinical Medical College, Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing 210046, China;
2.Department of Gastroenterology, Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Jiangsu Province, Nanjing 210028, China |
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Abstract Irritable bowel syndrome (IBS) is a kind of functional intestinal disorder, which, characterized by diarrhea, is called diarrhea predominant irritable bowel syndrome (IBS-D). Professor LU Min believes that the causes of IBS-D are aeipathia lost treatment, affect-mind dissatisfaction and improper diet, which tend to liver dysfunction, spleen deficient, thus lead to liver qi invading spleen. In the clinical work, the method of supporting the spleen and restricting the liver supplemented by restoring normal coordination between heart and kidney is used to treat IBS-D and has obtained a remarkable therapeutic efficacy.
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[1] Drossman DA，Hasler WL. Rome Ⅳ-Functional GI Disorders: Disorders of Gut-Brain Interaction [J]. Gastroenterology，2016，150（6）：1257-1261.
[2] Lacy BE，Mearin F，Lin C，et al. Bowel Disorders [J]. Gastroenterology，2016，150（6）：1393-1407.
[3] Lovell RM，Ford AC. Global Prevalence of and Risk Factors for irritable bowel syndrome：A Meta-analysis [J]. Clin Gastroenterol Hepatol，2012，10（7）：712-721.
[4] 中华医学会消化病学分会胃肠动力学组.肠易激综合征诊断和治疗的共识意见（2007，长沙）[J].中华消化杂志，2008，28（1）：298-300.
[5] 姚欣，杨云生，赵卡兵，等.罗马Ⅲ标准研究肠易激综合征临床特点及亚型[J].世界华人杂志，2008，16（5）：563-566.
[6] Camilleri M，Lasch K，Zhou W. Irritable bowel syndrome：methods，mechanisms，and pathophysiology. The confluence of increased permeability，inflammation，and pain in irritable bowel syndrome [J]. Am J Physiol Gastrointest Liver Physiol，2012，303（4）：G775-G785.
[7] Pohl CS，Medland JE，Moeser AJ. Early Life Stress Origins of Gastrointestinal Disease：Animal Models， Intestinal Pathophysiology，and Translational Implications [J]. Am J Physiol Gastrointest Liver Physiol，2015，309（12）：G927-G941.
[8] Katsumata R，Shiotani A，Murao T，et al. Gender Differences in Serotonin Signaling in Patients with Diarrhea-predominant Irritable Bowel Syndrome [J]. Intern Med，2017， 56（9）：993-999.
[9] Yu FY，Huang SG，Zhang HY，et al. Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis [J]. World J Gastroenterol，2016，22（12）：3451-3459.
[10] Barshop K，Staller K. New Pathways，New Targets：Visceral Hypersensitivity Pathogenesis in Irritable Bowel Syndrome [J]. Clin Transl Gastroenterol，2016，7（2）：e146.
[11] Yoon H. Mast Cell May Be the Master Key to Solve the Mystery of Pathogenesis of Irritable Bowel Syndrome [J]. Gut Liver，2016，10（3）：325-326.
[12] Liu Y，Zhang L，Wang X，et al. Similar Fecal Microbiota Signatures in Patients With Diarrhea-predominant Irritable Bowel Syndrome and Patients With Depression [J]. Clin Gastroenterol Hepatol，2016，14（11）：1602-1611.
[13] Ishimoto H，Oshima T，Sei H，et al. Claudin-2 expression is upregulated in the ileum of diarrhea predominant irritable bowel syndrome patients [J]. J Clin Biochem Nutr，2017，60（2）：146-150.
[14] Wei H，Liu ZJ，Wang K，et al. The dietary features of diarrhea predominant irritable bowel syndrome patients with small intestinal bowel overgrowth [J]. Zhonghua Nei Ke Za Zhi，2017，56（8）：567-571.
[15] 中国中西医结合学会消化系统疾病专业委员会.肠易激综合征中西医结合诊疗共识意见[J].中国中西医结合杂志，2011，31（5）：587-590.
[16] 陆敏，谢慧，樊欣钰，等.“肠康方”治疗腹泻型肠易激综合征43例临床研究[J].江苏中医药，2015，47（11）：27-29.
[17] 李时珍.本草纲目[M].5版.北京：华夏出版社，2013：589-592.
[18] 叶天士.本草经解[M].北京：学苑出版社，2011：29-30.
[19] 兰茂.滇南本草[M].北京：中国中医药出版社，2013：24-25.
[20] 汪昂.医方集解[M].上海：中国医药科技出版社，2011：76. |
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