皮内针调理肝肺法治疗慢性难治性咳嗽的临床效果

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Abstract Objective To study the clinical effect of treating chronic refractory cough with intradermal needle regulating liver and lung. Methods According to Excel, a random number table was generated, and the 24 patients diagnosed as liver fire invading lung type chronic refractory cough in the outpatient clinic of Guang′anmen Hospital, China Academy of Chinese Medical Sciences from June 2015 to March 2016 were divided into treatment group and control group by random, controlled and single blind method, with 12 cases in each group. Both groups were given basic treatment, on this basis, the treatment group was given intradermal needle treatment, and the control group was given true acupoint comfort needle treatment. Treatment was performed for four weeks, and one follow-up was performed after four weeks of treatment. Cough symptom score, Leicester cough questionnaire (LCQ) and cough visual analogue scale (VAS) scores were used as the main evaluation indicators. Results During the study, three cases of abscission, two cases of loss of follow-up, one case of business trip and the remaining nine cases were in the control group. Cough symptom scores: there were statistically significant differences in the time points and the interaction of daytime cough between the two groups (all P ＜ 0.05), but no statistically significant differences between the two groups (P ＞ 0.05). The differences of night cough score at time points were statistically significant (all P ＜ 0.05), while the differences between the two groups and interaction were not statistically significant (all P ＞ 0.05). Intra-group comparison: after four weeks of treatment and four weeks after the end of the treatment course, the scores of daytime cough and night cough in the treatment group were all lower than those before treatment, and the scores of night cough in the control group were lower than those before treatment (all P ＜ 0.05). VAS score: there were statistically significant differences in the scores of cough degree and cough frequency between groups and at time points (all P ＜ 0.05), but no statistically significant difference in the interaction (P ＞ 0.05). The differences of night cough score at time point were statistically significant (all P ＜ 0.05), while the differences between the two groups and interaction were not statistically significant (all P ＞ 0.05). Intra-group comparison: after four weeks of treatment and four weeks after the end of treatment course, cough degree, cough frequency and night cough score of the two groups were all lower than those before treatment (all P ＜ 0.05). Comparison between groups: after four weeks of treatment and four weeks after the end of treatment course, the scores of cough degree and cough frequency in the treatment group were lower than those in the control group (all P ＜ 0.05). LCQ scores: there were statistically significant differences in the time points of the physiological, psychological and social part scores (P ＜ 0.05), while the differences between the two groups and interaction were not statistically significant (all P ＞ 0.05). There were no statistically significant differences between the two groups, time points and interaction in the total score (all P ＞ 0.05). Intra-group comparison: after four weeks of treatment and four weeks after the end of treatment course, the treatment group physical parts, psychological part, social part scores were higher than those before treatment, the differences were statistically significant (all P ＜ 0.05), four weeks after the end of treatment course, the control group psychological part, social part scores were higher than those before treatment, the differences were statistically significant (all P ＜ 0.05). Conclusion Intradermal needle is safe and effective in treating chronic refractory cough. The therapeutic effect is mainly reflected in reducing the severity and frequency of cough.

Key words： Intradermal needle Refractory cough Cough visual analogue scale Leicester cough questionnaire Cough symptom score

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	LIU Zhiguo1
	2 LI Haixia3 WANG Lei1 BIAN Yongjun1 LI Guangxi1 LI Guoqin1 RONG Yi1 KANG Xiuhong4▲

Cite this article:

LIU Zhiguo1,2 LI Haixia3 WANG Lei1 BIAN Yongjun1 LI Guangxi1 LI Guoqin1 RONG Yi1 KANG Xiuhong4▲. Clinical effect of treating chronic refractory cough with intradermal needle regulating liver and lung[J]. 中国医药导报, 2020, 17(30): 173-177.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I30/173

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