基于名医验案探讨卵巢早衰用药规律

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Abstract Objective To collect cases of premature ovarian failure (POF) treated by famous traditional Chinese medicine doctors, and to analyze the rules of formulating prescriptions, to provide reference for the selection of prescriptions and ideas for clinical treatment. Methods A computer search of proven records of famous doctors in treating POF included in the China National Knowledge Infrastructure (CNKI) database, with the subject term “premature ovarian failure” searched for documents collected from the establishment of the database until February 2020. Statistical analysis based on the frequency of drug use, nature and flavour, channel tropism of the drugs and the results of Apriori association rules as observation indicators. Results A total of 103 papers and 112 prescriptions were included, and 165 herbs were involved. The herbs listed in usage frequency from high to low were Radix Rehmanniae Preparata, Semen Cuscutae, Radix Angelicae Sinensis, Herba Epimendii, Fructus Lycii. Four nature of drugs listed from high to low were warm, clam, cold, cool, hot. The proportion of five flavors from high to low were sweet, bitter, pungent, sour, astringent, salty, tasteless. The frequency of drug used in descending order were liver, kidney, spleen, lung, heart. Apriori association rules showed that the highest rule support were Radix Rehmanniae Preparata combined with Radix Angelicae Sinensis, Radix Rehmanniae Preparata combined with Radix Angelicae Sinensis and Semen Cuscutae. Conclusion The mainly etiology of POF are deficiency of kidney and sometimes with stagnation of liver and blood stasis. The disease is intermingled deficiency and excess, mainly deficiency. The treatment principles are strengthening and nourishing marrow and essence, and combined with benefiting qi and nourishing blood, and dispersing stagnated liver qi.

Key words： Premature ovarian failure Data mining Literature research Association analysis

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	LI Lan ZHONG Dayuan YANG Kaifeng XIAO Xiaoqin

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LI Lan ZHONG Dayuan YANG Kaifeng XIAO Xiaoqin. Exploration the medication rules of premature ovarian failure based on the proven records of famous doctors[J]. 中国医药导报, 2020, 17(30): 165-168.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I30/165

[1] Ghahremani-Nasab M，Ghanbari E，Jahanbani Y，et al. Premature ovarian failure and tissue engineering [J]. J Cell Physiol，2020，235（5）：4217-4226.
[2] Lew R. Natural history of ovarian function including assessment of ovarian reserve and premature ovarian failure [J]. Best Pract Res Clin Obstet Gynaecol，2019，55：2-13.
[3] Podfigurna-Stopa A，Czyzyk A，Grymowicz M，et al. Premature ovarian insufficiency：the context of long-term effects [J].J Endocrinol Invest，2016，39（9）：983-990.
[4] 卢军，陈燕芬，方米泥，等.仙胶合剂对肝肾阴虚型卵巢早衰患者骨代谢的影响[J].河南中医，2018，38（6）：941-944.
[5] 吴洁，陈蓉.早发性卵巢功能不全的激素补充治疗专家共识[J].中华妇产科杂志，2016，51（12）：881-886.
[6] 赵越，阮祥燕.间充质干细胞用于卵巢早衰患者生殖力保护的研究进展[J].中国临床医生杂志，2019，47（7）：771-774.
[7] Sullivan SD，Sarrel PM，Nelson LM. Hormone replacement therapy in young women with primary ovarian insufficiency and early menopause [J]. Fertil Steril，2016，106（7）：1588-1599.
[8] Reichman S，Slembrouck A，Gagliardi G，et al. Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions [J]. Stem Cells，2017，35（5）：1176-1188.
[9] Webber L，Davies MC，Anderson RA，et al. ESHRE Guideline：management of women with premature ovarian insufficiency [J]. Hum Reprod，2016，31（5）：926-937.
[10] 曾富玲，孙维峰，李静，等.活血滋肾方治疗肾虚血瘀型免疫性卵巢早衰临床观察[J].中国中西医结合杂志，2019， 39（5）：536-541.
[11] 尚玉洁，陈赟，卢苏.补肾活血中药治疗卵巢早衰的系统评价与Meta分析[J].中医杂志，2018，59（15）：1295-1299.
[12] 钟赣生.中药学[M].3版.北京：中国中医药出版社，2012：2-10.
[13] 韩红伟，张花，李林智，等.张迎春辨治卵巢早衰性不孕症经验[J].中医药临床杂志，2019，31（12）：2235-2238.
[14] 张彦，谈勇.交济心肾法在妇科疾病中的应用[J].山东中医杂志，2019，38（11）：1014-1017.
[15] 郭婧，肖潇，姚海洋，等.滕秀香教授从肝论治早发性卵巢功能不全经验[J].中国临床医生杂志，2019，47（7）：876-877.
[16] 袁爱倩，赵粉琴.基于精血同源探究左归丸治疗卵巢储备功能低下所致月经过少的诊疗思路[J].中医药学报，2019，47（6）：59-62.
[17] 卢如玲.张玉珍教授治疗绝经前后诸症之经验[J].环球中医药，20181（7）：1048-1049.
[18] 齐玉，王翠霞.从脾论治卵巢早衰[J].亚太传统医药，2019，15（12）：111-113.
[19] 曹晓静，王小云.王小云辨治卵巢早衰经验[J].中医杂志，2015，56（5）：372-375.
[20] 吴丽婷，石玥，刘雁峰，等.肖承悰治疗卵巢早衰经验[J].中医杂志，2017，58（2）：108-110.
[21] 刘丹，姚海洋，滕秀香.国医大师柴松岩闭经验案举隅[J].中国生育健康杂志，2020，31（1）：60-63.
[22] 徐小芳，金志春.金志春辨治卵巢早衰性不孕症的临证经验[J].中西医结合研究，2019，11（1）：45-47，53.
[23] 张爽，雷磊.雷磊教授治疗白血病患者化疗后卵巢早衰经验[J].中国中医药现代远程教育，2019，17（9）：31-34.
[24] 朱一波，王昕.中西医生殖轴在排卵机制中的共性及应用探析[J].亚太传统医药，2016，12（21）：84-86.
[25] 闫朋宣，杜宝俊，罗然.中药类激素样作用研究进展[J]. 中华中医药杂志，2014，29（2）：531-534.
[26] 孙美娜，韩延华.韩延华教授治疗肾虚血瘀型卵巢早衰经验总结[J].中国医药导报，2020，17（1）：142-145.