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Progress of gastrointestinal motility effects on prevention and treatment in obesity with insulin resistance |
WANG Wenyan1,2 LIANG Fengxia2 |
1.Department of Acupuncture-Moxibustion, Wuhan Hospital of Traditional Chinese Medicine, Hubei Province, Wuhan 430014, China;
2.College of Acupuncture-Moxibustion and Orthopedics, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430061, China |
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Abstract Abnormal gastrointestinal motility is an important pathological factor of obesity with insulin resistance. Abnormal gastrointestinal motility not only make the body excessive intake of energy, but also can produce the intestinal inflammation, affect information exchanges of brain-gut axis, then reduce insulin sensitivity, and reduce energy consumption relatively, which eventually lead to imbalances in the body′s energy metabolism. Therefore, it may be a new approach to prevent and treat insulin-resistant obesity to set about gastrointestinal motility and develop treatment for various factors affecting gastrointestinal motility, such as inflammation, intestinal flora and enteric nervous system.
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