维甲酸协同砷剂治疗急性早幼粒细胞白血病的机制进展

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Abstract Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia. The first-line treatment for APL patients is retinoic acid (RA) combined with arsenic at present. There has been some new research achievement about the mechanism of RA and arsenic in the treatment of APL appeared in molecular biology and cytogenetics in the past five years. This article mainly describes the changes of additional genes, non-genetic molecular mechanisms, mechanisms of combined drug, adjuvants and carriers, so as to provide a reference for future basic research.

Key words： Acute promyelocytic leukemia Retinoic acid Arsenic Mechanism

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	LIU Feng DONG Min XIAO Dinghua

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LIU Feng DONG Min XIAO Dinghua. Mechanism of Retinoic acid combined with arsenic in the treatment of acute promyelocytic leukemia[J]. 中国医药导报, 2020, 17(30): 45-48.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I30/45

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