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Systematic evaluation of the prevalence of hyperuricemia in the elderly in China |
YANG Ting1 WANG Shurui1 WANG Ruirui1 WEI Wentong1 YANG Xueshi1 ZHANG Chunmei2 |
1.Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;
2.School of Nursing, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
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Abstract Objective To systematically evaluate the incidence of hyperuricemia (HUA) in the elderly in China from 2010 to 2019. Methods PubMed, EMbase, Web of Science, CNKI, WanFang Data, VIP and CBM databases were electronically searched to collect cross-sectional studies on the prevalence of HUA of Chinese elderly from January 2010 to December 2019. Two reviewers independently screened literature, extracted data and assessed risk of bias of included studies. Then, meta analysis was performed by using Stata 12.0 software. Results A total of 31 cross-sectional studies and 110 103 elderly were included. Meta-analysis showed that the overall prevalence of HUA in Chinese elderly was 21% (95%CI[18%, 24%]), in which 22% (95%CI[20%, 25%]) was male and 19% (95%CI[15%, 22%]) was female. The prevalence of HUA was 19% (95%CI[14%, 24%]) in the elderly aged 60, <70, 26% (95%CI[20%, 31%]) in the elderly aged 70, <80 and 29% (95%CI[20%, 38%]) in the elderly aged ≥80. The prevalence of HUA was 22% (95%CI[19%, 26%]) in coastal areas, and 18% (95%CI[13%, 23%]) in inland areas. By using the diagnostic criteria proposed by Chinese expert consensus on hyperuricemia and gout treatment, the prevalence of HUA was 28% (95%CI[19%, 38%]), and was 18% (95%CI[10%, 26%]) using the criteria of the eighth edition of Internal Medicine. Conclusion The prevalence of HUA in the elderly in China is relatively high. The prevalence of HUA is different in the elderly with different gender, age and geographical location, and the prevalence of HUA is significantly different with different diagnostic criteria.
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