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Analysis of breast cancer screening results of 24 693 people of physical examination combined with ultrasound and selective complementary mammography |
DING Songtao MA Xiangjun▲ HE Xiangping CHEN Si ZHANG Yi QIN Jing |
Center for Prevention and Treatment of Breast Diseases, Maternal and Child Health Hospital of Haidian District, Beijing 100080, China |
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Abstract Objective To evaluate the application value of physical examination combined with ultrasound and selective supplemental mammography for breast cancer screening. Methods From June 2013 to December 2016, 24 693 women of appropriate age who underwent breast cancer screening in Maternal and Child Health Hospital of Haidian District of Beijing were selected as the study subjects. Mammography rate, detection rate of breast cancer and early breast cancer, recall rate of biopsy, rate of biopsy, biopsy compliance rate, biopsy positive predictive value (PPV) were analyzed. The detection rate of breast cancer and early breast cancer before and after supplementary mammography were compared. The correlation between the detection rate of early breast cancer and the rate of mammography examination and biopsy compliance were analyzed. Results A total of 7211 (29.20%) people underwent supplementary mammography. Before supplemental mammography, 54 cases (bilateral breast cancer were recorded two cases) of breast cancer were detected, and the detection rate of breast cancer was about 218.69/100 000. Among them, 33 cases of early stage breast cancer and the detection rate of it was about 133.64/100 000. Ten cases of breast cancer were detected after supplemental mammography, including nine cases of early breast cancer, the detection rate of breast cancer was about 259.18/100 000, and the detection rate of early breast cancer was about 170.09/100 000. There were no significant differences between the detection rate of breast cancer and early breast cancer before and after supplemental mammography (P > 0.05). A total of 460 people(1.86%) were recalled for biopsy after the screening, and the actual biopsy was 121 people (0.49%), the biopsy compliance rate was about 26.30%, and the biopsy PPV was about 52.89%. The detection rate of early breast cancer was significantly positively correlated with the biopsy compliance rate (r = 0.996, P < 0.01), but not with the mammography detection rate (P > 0.05). Conclusion The screening mode of physical examination combined with ultrasound and selective supplement mammography for breast cancer screening is effective and feasible, but the standards of supplementary mammography should be optimized. The biopsy compliance rate after screening need to be improved.
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