CEUS评价颈动脉硬化斑块内新生血管与脑梗死患者NIHSS及mRs评分的关系

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Abstract Objective To investigate the relationship between contrast-enhanced ultrasound (CEUS) evaluation of neovascularization in carotid atherosclerotic plaques and the National Institutes of Health stroke scale (NIHSS) score and the modified Rankin scale (mRs) score in patients with acute cerebral infarction. Methods The clinical data of 148 patients with acute ischemic cerebral infarction admitted to the Huai′an First Hospital Affiliated to Nanjing Medical University from October 2016 to October 2019 were retrospectively analyzed. According to the presence or absence of carotid atherosclerotic plaque, those without plaque were admitted to group A (41 cases). The other 107 patients had plaque and received CEUS. According to the results of CEUS (plaque classification), the patients were divided into group B (stable plaque, plaque classification of 0-Ⅰ, 19 cases) and group C (vulnerable plaque, plaque classification of Ⅱ-Ⅲ, 88 cases). The both sides of angiography grade of carotid artery plaques in patients with acute cerebral infarction with carotid atherosclerotic plaque were observed, and the NIHSS and mRs scores of the three groups and their correlation with the grade of neovascularization in carotid atherosclerotic plaque were analyzed. Results Comparison of both sides of the angiographic grading of carotid artery plaques in patients with carotid atherosclerotic plaque showed no statistically significant difference (P ＞ 0.05). Comparison of NIHSS and mRs scores between groups A and B showed no statistically significant differences (P ＞ 0.05). NIHSS and mRs scores in groups A and B were lower than those in group C, and the differences were statistically significant (P ＜ 0.05). NIHSS and mRs scores in patients with acute cerebral infarction were positively correlated with the grade of neovascularization in carotid atherosclerotic plaque (r = 0.448, 0.406, all P ＜ 0.05). Conclusion CEUS evaluation of neovascularization in carotid atherosclerotic plaques is closely related to NIHSS and mRs scores in patients with acute cerebral infarction.

Key words： Contrast-enhanced ultrasound Plaque neovascularization Acute cerebral infarction National Institutes of Health stroke scale Modified Rankin scale

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	HUANG Hui SHENG Wenwei▲

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HUANG Hui SHENG Wenwei▲. CEUS evaluation of the relationship between neovascularization in carotid atherosclerotic plaque and NIHSS and mRs scores in patients with cerebral infarction[J]. 中国医药导报, 2020, 17(29): 73-76.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I29/73

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