吲哚氰绿清除试验在乙型肝炎肝硬化诊断中的临床意义

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Abstract Objective To study the clinical significance of indocyanine green excretion test in the diagnosis of patients with hepatic B liver cirrhosis. Methods The clinical data of 275 patients with hepatitis B (chronic hepatitis B group) and 306 patients with hepatic B liver cirrhosis (hepatitis B liver cirrhosis group) in the Sixth People's Hospital of Qingdao from June 2016 to July 2017 was analyzed retrospectively. The indole cyanogen green (ICG) discharge tested, liver stiffness detection and abdominal ultrasonography were carried out in the two groups. Results Compared with chronic hepatitis B group, T1/2,R15 value and E value was increased in hepatic B liver cirrhosis group, and the K value was decreased, the differences were statistically significant (P < 0.05). K value and CAP value were negatively correlated with the degree of liver sclerosis (r = -0.672, -0.826, all P < 0.05), R15 value was positively correlated with the degree of liver sclerosis (r = 0.891, P < 0.05). Conclusion Indocyanine green test is helpful to evaluate the liver sclerosis, as a supplement to Fibroscan, and can be the new indication and method to investigate the degree of liver sclerosis.

Key words： Indocyanine green excretion test Hepatic B liver cirrhosis Hepatitis B Fibroscan

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	GUO Lu CHEN Xiaoli WANG Dexin YAN Xiuping

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GUO Lu CHEN Xiaoli WANG Dexin YAN Xiuping. Clinical significance of indocyanine green clearance test in the diagnosis of hepatitis B liver cirrhosis[J]. 中国医药导报, 2018, 15(1): 57-59,94.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2018/V15/I1/57

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