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Retrospective analysis of 36 AIDS patients in Junchuan Country, Hubei Province |
ZHAO Xin1 YANG Yi2 NI Wei3 |
1.College of Chinese Clinical Medicine, Hubei University of Chinese Medicine, Hubei Province, Wuhan 430061, China;
2.Department of Pulmonology, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province, Wuhan 430061, China;
3.Department of Clinical Laboratory, Hubei Provincial Hospital of Traditional Chinese Medicine Hubei Provincial Academy of Traditional Chinese Medicine, Hubei Province, Wuhan 430074, China |
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Abstract Objective To retrospectively analyze the population characteristics of 36 patients with acquired immune deficiency syndrome (AIDS) combined with cough (type of phlegm-fever stagnating in the lung) diagnosed by traditional Chinese medicine syndrome differentiation in Junchuan Country, Hubei Province, and to explore whether there was any difference in the number of peripheral blood cells in patients with AIDS combined with cough of different physique was discussed. Methods July 2017 to February 2018, the implementation unit of the National Traditional Chinese Medicine Treatment AIDS Pilot Project in Wenxinjiayuan, Junchuan Town, Hubei Province, a total of 36 cases who were diagnosed with AIDS combined with cough (phlegm-heat-stagnation lung type) traditional Chinese medicine diagnosis and treatment plan clinical verification study were collected and consulted, while the original medical records of each patient were statistically analyzed by descriptive epidemiological methods. At the same time, according to the classification standard of Chinese body mass index, the test population were divided into the lean group (6 cases), the normal group (24 cases) and the overweight group (6 cases). The single factor variance analysis was used to compare the levels of CD4+T lymphocytes, platelets and white blood cells in the three groups. Results The 36 AIDS patients with cough (phlegm-heat stagnation lung type) were mostly middle-aged and elderly patients. The main route of infection was blood, and the level of AIDS awareness was low. Comparison of platelets and white blood cells of the three groups showed statistically significant differences (P < 0.05). Further pairwise comparisons, the platelets of lean group and the overweight group were higher than that of the normal group, and the differences were statistically significant (P < 0.05), while the white blood cells of lean group was higher than that of the normal group and the overweight group, and the differences were statistically significant (P < 0.05). Conclusion The screening, education and publicity of middle-aged and elderly people with lower cultural level should be intensified, and effective treatment and prevention and control measures should be implemented as soon as possible. In clinical work, attention should be paid to the impact of physical factors on AIDS patients, so as to formulate and improve more reasonable diagnosis and treatment plans, and provide new ideas for better treatment of AIDS patients.
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[1] 2019年我国艾滋病防治工作取得新进展[J].中国艾滋病性病,2019,25(12):1205
[2] 石修业,周沛林,郭芳,等.2008—2014年随州市艾滋病主动监测工作探讨[J].公共卫生与预防医学,2016,27(3):85-87.
[3] 陈国春,卫峥,马波,等.艾滋病患者高效抗病毒治疗后免疫重建及预后影响因素的研究[J].中华医院感染学杂志,2018,28(22):63-66.
[4] Arseniou S,Arvaniti A,Samakouri M. HIV infection and depression [J]. Psychiatry Clin Neurosciences,2014,68(2):96-109.
[5] 李太生,王福生,高福.中国艾滋病诊疗指南(2018版)[J].新发传染病电子杂志,2019,4(2):65-84.
[6] 中华医学会呼吸病学分会哮喘学组.咳嗽的诊断与治疗指南(2015)[J].中华结核和呼吸杂志,2016,39(5):323-354.
[7] 周仲英.中医内科学[M].2版.北京:中国中医药出版社,2012.
[8] 中华人民共和国国家标准 中医临床诊疗术语疾病部分(续上期)[J].成都中医药大学学报,1998(2):53-55.
[9] 危剑安.中医药治疗艾滋病临床技术方案(试行)[C].中国中西医结合学会传染病专业委员会.第一次全国中西医结合传染病学术会议论文汇编.中国中西医结合学会传染病专业委员会:中国中西医结合学会,2006:504-507.
[10] 季兰芳.成人体质指数对照表的研制及其应用说明[J].金华职业技术学院学报,2008,8(6):50-51.
[11] 常亮,施学忠,谢婧,等.河南省艾滋病高发区居民艾滋病相关知识水平及其影响因素分析[J].现代预防医学,2009,36(15):2801-2804.
[12] 徐新民,李敏,李瑞红,等.艾滋病合并呼吸道感染患者的病原菌分布及药敏分析[J].标记免疫分析与临床,2019, 26(5):830-832,879.
[13] 陈燕萍,杨春,王芳,等.血清IFN-γ和IL-10及免疫球蛋白与艾滋病患者机会性感染的关系研究[J].中华医院感染学杂志,2017,27(20):4595-4598.
[14] 张兰兰.CRP和白细胞计数联合检验在感染诊断中的应用[J].中外女性健康研究,2019(20):100-101.
[15] 肖科,曹汴川,罗瑜,等.艾滋病合并血流感染病人预后不良的危险因素[J].中国艾滋病性病,2019,25(7):691-694.
[16] Rebecca J,Fischetti BS,Kavanagh RK,et al. Safety and Efficacy of Weight-Loss Pharmacotherapy in Persons Living with HIV:A Review of the Literature and Potential Drug-Drug Interactions with Antiretroviral Therapy [J]. Pharmacotherapy,2019,39(12):1204-1215.
[17] Zheng XJ,Yang ZX,Dong YJ,et al. Downregulation of leptin inhibits growth and induces apoptosis of lung cancer cells via the Notch and JAK/STAT3 signaling pathways [J]. Biol Open,2016,5(6):794-800.
[18] Procaccini C,La Rocca C,Carbone F,et al. Leptin as immune mediator:Interaction between neuroendocrine and immune system [J]. Dev Comp Immunol,2017,66:120-129.
[19] Cava AL,Matarese G. The weight of leptin in immunity [J]. Nat Revi Immunol,2004,4(5):371-379
[20] Madssen E,Skaug EA,Wisl?覬ff U,et al. Inflammation Is Strongly Associated With Cardiorespiratory Fitness,Sex,BMI,and the Metabolic Syndrome in a Self-reported Healthy Population:HUNT3 Fitness Study [J]. Mayo Clin Proc,2019,94(5):803-810.
[21] 徐梦丹,戴秋艳.炎症与肥胖相关性高血压研究进展[J].国际心血管病杂志,2015,42(6):372-375.
[22] Kim TN,Park MS,Lim KIL,et al. Relationships between Sarcopenic Obesity and Insulin Resistance,Inflammation,and Vitamin D Status:The Korean Sarcopenic Obesity Study (KSOS) [J]. Clin Endocrinol (Oxf),2013,78(4):525-532.
[23] 石文升.血小板相关参数与凝血指标在肝硬化疾病中的应用探讨[J].中国现代医生,2019,57(36):23-25.
[24] 张文莹,张小河.血小板计数在肺结核诊断中的应用研究[J].中国实用医药,2019,14(25):196-197.
[25] 邱彩玲,卢建坤,吴品,等.血小板参数在妊娠期糖尿病诊断中的临床意义[J].中国医学创新,2018,15(18):7-10.
[26] Voudoukis E,Karmiris K,Koutroubakis IE. Multipotent role of platelets in inflammatory bowel diseases:A clinical approach [J]. World J Gastroenterol,2014,20(12):3180-3190. |
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