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Research progress in the relationship between 3-nitrotyrosine and diabetic vascular disease |
ZHAO Ruohan1 WANG Lixin2▲ TIAN Fengsheng3 BAI Hailong3 |
1.Graduate School, Hebei University of Chinese Medicine, Hebei Province, Shijiazhuang 050091, China;
2.Department of Government Affairs, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Hebei University of Chinese Medicine, Hebei Province, Cangzhou 061001, China;
3.Department of Endocrine Diabetes, Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Hebei University of Chinese Medicine, Hebei Province, Cangzhou 061001, China |
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Abstract Vascular disease is one of the chronic complications of diabetes, basically involves the heart, the kidney, the peripheral blood vessel, the eye and so on. As the disease progresses, oxidative stress reaction aggravates, and promote the conversion of protein tyrosine residues to 3-nitrotyrosine. The increase of 3-nitrotyrosine exacerbates occurrence and development of diabetic vascular disease as well, and attracted more and more people′s attention. For the past few years, there are more and more studies on 3-nitrotyrosine in Chinese and Westerm medicine. This article reviews the recent advances in the study of relationship between 3-nitrotyrosine and diabetic vascular disease. It provides a possibility for the effective prevention and treatment of diabetic vascular disease.
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