|
|
Value of two dimensional shear wave elastography in differential diagnosis of cervical lymph nodes with different pathological types |
LIANG Kui WANG Xiaorong SONG Tao |
Department of Abdominal Ultrasound, the First Affiliated Hospital of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi 830054, China |
|
|
Abstract Objective To investigate the differential diagnosis value of two dimensional shear wave elastography (2D-SWE) in different pathological types of cervical lymph nodes. Methods A total of 101 patients with 145 enlarged cervical lymph nodes from October 2017 to May 2019 in the First Affiliated Hospital of Xinjiang Medical University were selected, and they underwent routine ultrasound and 2D-SWE examination. They were grouped according to lymph node pathology or results after six months of follow-up. Nodal tuberculosis, lymphoma and metastatic lymph nodes were selected as the case group (92 cases) and reactive hyperplasia lymph nodes as the control group (53 cases). Binary logistic regression was used to screen the elastic parameter with high differential value between the case group and the control group, and the diagnostic boundary value was determined by the comparison of this parameter between the groups and the ROC curve. Results Binary logistic regression showed that lymph node blood flow type, internal echo and 2D-SWE parameter Emax had higher differential diagnostic value between the case group and the control group. The Emax values of lymphomas, nodal tuberculosis and metastatic lymph nodes were higher than those of reactive hyperplasia lymph nodes (all P < 0.01) and increased step by step. The Emax boundary value of lymphomas and reactive hyperplasia lymph nodes was 30.0 kPa (P < 0.01), and the AUC, sensitivity and specificity were 0.783, 78.57% and 67.92%, respectively. The Emax boundary value of nodal tuberculosis and lymphoma was 47.53 kPa (P < 0.01), and the AUC, sensitivity and specificity were 0.856, 71.43% and 91.30%, respectively. There was no significant difference in Emax value between reactive hyperplasia lymph nodes and nodal tuberculosis (P > 0.05). Conclusion The 2D-SWE parameter Emax is the preferred elastic parameter to reflect the difference in hardness of cervical lymph nodes of different pathological types, which can be used as an important supplementary indicator for the ultrasonic differential diagnosis of cervical lymph node diseases.
|
|
|
|
|
[1] 宋爽,张麒,韩红,等.基于特权信息学习的淋巴结病变计算机辅助诊断[J].自动化仪表,2019,40(12):61-65.
[2] 葛喜凤,李磊,崔立刚,等.超声弹性对比指数在淋巴结良恶性鉴别诊断中的应用价值[J].中国医学科学院学报,2018,40(5):680-684.
[3] 李强.超声剪切波弹性成像的技术进展[J].中国医疗设备,2017,32(7):101-105,123.
[4] Desmots F,Fakhry N,Mancini J,et al. Shear Wave Elastography in Head and Neck Lymph Node Assessment:Image Quality and Diagnostic Impact Compared with B-Mode and Doppler Ultrasonography [J]. Ultrasound Med Biol,2016,42(2):387-398.
[5] Choi YJ,Lee JH,Lim HK,et al. Quantitative shear wave elastography in the evaluation of metastatic cervical lymph nodes [J]. Ultrasound Med Biol,2013,39(6):935-940.
[6] Dudea SM,Lenghel M,Botar-Jid C,et al. Ultrasonography of superficial lymph nodes:be-nign vs. Malignant [J]. Med Ultrason,2012,14(4):294-306.
[7] 冉飞武,李建彬,梁超前,等.头颈部肿瘤颈部淋巴结分区及其靶区的勾画[J].中华放射肿瘤学杂志,2005,14(6):528-534.
[8] 中华医学会超声医学分会介入超声学组弹性成像评估肝纤维化专家组.二维剪切波弹性成像评估慢性乙型肝炎肝纤维化临床应用指南[J].临床肝胆病杂志,2018,34(2):255-261.
[9] 阮镜良,梁铭,吴嘉怡,等.淋巴结大小对剪切波弹性定量参数诊断价值的影响[J].中国超声医学杂志,2017,33(6):492-494.
[10] Bhatia KS,Cho CC,Tong CS,et al. Shear Wave Elasticity Imaging of Cervical Lymph Nodes [J]. Ultrasound Med Biol,2012,38(2):195-201.
[11] 王晓荣,刘霞,姚兰辉,等.颈部淋巴结淋巴瘤皮质回声及其病理基础的初步探讨[J].中国超声医学杂志,2013, 29(8):676-680.
[12] Fukuhara T,Matsuda E,Endo Y,et al. Impact of Fibrotic Tissue on Shear Wave Velocity in Thyroid:An Ex Vivo Study with Fresh Thyroid Specimens [J]. Biomed Res Int,2015,2015:569367.
[13] 轩维锋,张建兴,崔立刚,等.浅表组织超声与病理诊断[M].北京:人民军医出版,2015:141-180.
[14] 赵奕文,金正吉,郑颖,等.颈淋巴结结核的超声表现与分型[J].上海医学影像,2008,17(3):218-219,封三.
[15] 张更臣,李俊来,曹兵生,等.颈部淋巴结结核超声表现与病理对照研究[J].中国超声医学杂志,2013,29(10):879-882.
[16] 白智群,王学梅,黄崑,等.剪切波弹性成像在颈部淋巴结结核诊断及鉴别诊断中的价值[J].中国超声医学杂志,2018,34(10):874-877.
[17] 陈顺军,宋乐乐,贺军领,等.剪切波弹性成像诊断甲状腺癌术后经131I治疗后颈部淋巴结良恶性的价值[J].中国医学影像学杂志,2019,27(2):128-130.
[18] 江建伟,陈曼.超声弹性成像联合常规超声对淋巴瘤性浅表淋巴结肿大的应用价值[J].中国医学计算机成像杂志,2019,25(2):176-180.
[19] 赵大卫,王明正,刘佳坤,等.功能性颈淋巴结清扫术治疗颈部淋巴结核的疗效观察[J].疑难病杂志,2019,18(1):52-56.
[20] 赵跃,刘春蓉,张桐硕,等.基于危险因素构建的Logistic回归模型对甲状腺乳头状癌颈部淋巴结转移的预测价值研究[J].中国医药,2019,14(2):282-286.
[21] 刘旭,陈晓艳.剪切波弹性成像预测甲状腺乳头状癌颈部淋巴结转移的价值[J].广东医学,2019,40(5):729-731,735.
[22] 王思思,王波,谢超,等.甲状腺乳头癌淋巴结转移与甲状腺球蛋白的关系[J].中国医药导报,2018,15(35):114-117.
[23] 张雪云,聂芳,吕文豪,等.超声造影对结核性淋巴结与转移性淋巴结的鉴别诊断价值[J].中国超声医学杂志,2018,34(5):403-406.
[24] 黄琨,李玉丹,包明稳,等.高频超声检查在颈部异常淋巴结中的诊断价值[J].中国医药科学,2019,9(23):231-233.
[25] Tan S,Miao LY,Cui LG,et al. Value of Shear Wave Elastography Versus Contrast-Enhanced Sonography for Differentiating Benign and Malignant Superficial Lymphadenopathy Unexplained by Conventional Sonography [J]. J Ultrasound Med,2017,36(1):189-199.
[26] 马玉峰,张昕,张微,等.Q-box手动描绘模式剪切波弹性成像对乳腺癌新辅助化疗后腋窝淋巴结转移的早期预测[J].中国医学创新,2018,15(26):129-133.
[27] 杜宗艳,孙咏梅,宁春平,等.不同ROI和弹性模量值对剪切波弹性成像诊断颈部良恶性淋巴结效能的影响[J].中国医学影像技术,2019,35(1):50-54.
[28] 赵颖燕,奚佳颖,蒋海波,等.VTIQ技术对不同病理类型的鼻咽癌颈部转移性淋巴结的诊断价值回顾性研究[J].中国超声医学杂志,2018,34(9):772-774.
[29] 乔晓慧,刑晋放.剪切波超声弹性成像的原理及临床应用现状[J].中国介入影像与治疗学,2015,12(8):512-515. |
|
|
|