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| Application effect of Qige Huayu Decoction in the treatment of gastroesophageal reflux after esophageal cancer stent implantation |
| XU Yapei1 YANG Qian2 YANG Zhufeng1 DUAN Yangyang1 LI Bolin2 ZHAO Danyang2 |
1.Department of Gastroenterology, Hebei Hospital of Traditional Chinese Medicine, Hebei Province, Shijiazhuang 050011, China;
2.Department of Spleen and Stomach Diseases, Hebei Hospital of Traditional Chinese Medicine, Hebei Province, Shijiazhuang 050011, China |
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Abstract Objective To investigate application effect of Qige Huayu Decoction in the treatment of gastroesophageal reflux after esophageal cancer stent implantation. Methods Forty-six patients with gastroesophageal reflux after stent implantation in Hebei Hospital of Traditional Chinese Medicine from June 2017 to August 2018 were selected and divided into two groups according to random number table method. Control group (23 cases) was given Rabeprazole Sodium Enteric-coated Capsules orally, while treatment group (23 cases) was treated with Qige Huayu Decoction. Both groups were treated for four weeks. The symptom score of gastroesophageal reflux, clinical efficacy and gastroscopy efficacy of two groups were observed. Medical outcomes study short form-36 (SF-36) was used to evaluate the quality of life in patients. Results The scores of gastroesophageal reflux symptoms in two groups after treatment were lower than those before treatment, and treatment group was lower than that in control group, the differences were statistically significant (P < 0.05). There was no significant difference in total effective rate between two groups (P > 0.05). There was no significant difference in total effective rate of gastroscopy between two groups (P > 0.05). The physical pain and mental health scores of two groups after treatment were higher than those before treatment, and treatment group was higher than that in control group, the differences were statistically significant (P < 0.05). Conclusion Qige Huayu Decoction can effectively alleviate the symptoms, improve the degree of esophageal mucosal injury and improve the quality of life in patients with gastroesophageal reflux after stent implantation of esophageal cancer. Its clinical efficacy is better than that of Western medicine alone.
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