超声造影联合超声组织触诊技术对TI-RADS 4类甲状腺结节良恶性的诊断价值

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Abstract Objective To investigate the diagnostic value of contrast-enhanced ultrasound (CEUS) score combined with ultrasound tissue palpation in thyroid imaging report and data system (TI-RADS) type 4 thyroid nodule. Methods A total of 62 patients with thyroid nodules of TI-RADS type 4 in Qinghai Provincial People′s Hospital were selected as the research objects. CEUS, virtual touch tissue imaging (VTI) and virtual touch tissue imaging quantification (VTIQ) were performed preoperatively and shear wave velocity (SWV) was obtained. The receiver operating characteristic curve was drawn with pathology results as the gold standard, and the area under the curve (AUC) was compared to evaluate the diagnostic value of single application and combined application of the three methods for TI-RADS type 4 nodules. Results There were 66 nodules, 45 malignant nodules and 21 benign nodules. The cutoff value of CEUS score was four scores, and the sensitivity, specificity and accuracy were 86.7%, 81.0% and 84.8%, respectively. Ⅳ level for VTI cutoff value, sensitivity, specificity and accuracy were 84.4%, 81.0% and 83.3%, respectively. The average value of SWV in VTIQ technology was 2.70 m/s as the cutoff value and the sensitivity, specificity and accuracy were 80.0%, 85.7% and 81.8%, respectively. The sensitivity, specificity and accuracy of the combined application of the three methods were 93.3%, 85.7% and 90.9%, respectively. The AUC of the combination method, CEUS score, VTIQ technique and VTI were 0.952, 0.874, 0.847 and 0.800, respectively. The AUC of the combined method was the largest, and the sensitivity and accuracy of the combined method were higher than those of the single method, the differences were all statistically significant (all P ＜ 0.05). Conclusion CEUS score combined with VTI and VTIQ can significantly improve the determination of the thyroid nodule nature of TI-RADS 4, providing an imaging reference for the detection of malignant nodules.

Key words： Contrast-enhanced ultrasound Elastography Thyroid imaging reporting and data system Thyroid nodule

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	LI Na′na ZHANG Yuying YIN Qiuping MA Qinfeng CHEN Xianxia LI Rong YING Chunhua

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LI Na′na ZHANG Yuying YIN Qiuping MA Qinfeng CHEN Xianxia LI Rong YING Chunhua. Diagnostic value of contrast-enhanced ultrasound combined with ultrasound tissue palpation for benign and malignant thyroid nodules of TI-RADS type 4[J]. 中国医药导报, 2020, 17(22): 140-143.

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http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I22/140

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