|
|
Study on the prescription rule of Helicobacter pylori infection based on traditional Chinese medicine inheritance support system |
LIN Yishan1 JIANG Feng2 |
1.Beijing University of Chinese Medicine, Beijing 100029, China;
2.Department of Gastroenterology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China |
|
|
Abstract Objective To study the prescription rule of traditional Chinese medicine (TCM) in the treatment of Helicobacter pylori (Hp) infection. Methods The literatures of TCM in the treatment of Hp infection from CNKI and CQVIP were searched from January 2007 to January 2017, the recipe database was screened and set up, the TCM inheritance support system was used to carry out data mining, and the core drugs and its meridian tropism, prescription rules, core combination were analyzed. Results A total of 108 prescriptions about Hp infection were selected, including 159 herbs, and 30 drugs were used for more than 10 times. By analyzing the meridian tropism, TCM for Hp infection were mainly spleen and stomach meridian, followed by lung and liver meridian. Conclusion The Chinese medicine for the treatment of Hp is mainly clearing heat and removing toxicity, strengthening spleen and benefiting qi. The most frequent herbs for clearing heat and removing toxicity are Rhizoma Coptidis, Herba Taraxaci, etc, the most frequent herbs for strengthening spleen and benefiting qi are Radix Glycyrrhizae, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Poria, Radix Astragali seu Hedysari, etc.
|
|
|
|
|
[1] 汪荷,黄津芳,赵鸿雁,等.健康体检人群幽门螺旋杆菌感染状况调查[J].中国卫生统计,2012,29(5):734-736.
[2] 胡伏莲,成虹,张学智,等.多中心临床研究观察荆花胃康联合三联疗法治疗幽门螺旋杆菌相关性十二指肠溃疡和胃炎疗效及耐药分析[J].中华医学杂志,2012,92(10):679-684.
[3] 王平,田维毅,王文佳,等.黄芪含药血清对幽门螺杆菌空泡毒素活性的影响[J].西部中医药,2011,24(7):17-19.
[4] 徐艺,叶柏,单兆伟,等.中草药单味与复方对幽门螺旋杆菌抑制作用的实验研究[J].中国中西医结合脾胃杂志,2008,8(5):291-293.
[5] 吴玉梅,魏文珍,王平,等.黄连、吴茱萸有效组分不同配比体外抗幽门螺杆菌实验研究[J].贵阳中医学院学报,2014,36(6):21-23.
[6] 王平生,步许海,董德培.“幽菌消”治疗幽门螺旋杆菌感染60例临床观察[J].江苏中医,2000,21(4):8.
[7] 齐续林,高鹏飞,乔田奎,等.中药蒲公英抗肿瘤作用研究进展[J].中国肿瘤,2015,24(1):53-56.
[8] 魏华,彭勇,马国需,等.木香有效成分及药理作用研究进展[J].中草药,2012,3(43):613-620.
[9] 章斌,金剑,金芝贵,等.枳壳的药理作用与临床应用进展[J].医药导报,2013,32(11):1462-1464.
[10] 张淑洁,钟凌云.厚朴化学成分及其现代药理研究进展[J].中药材,2013,5(36):838-843.
[11] 王红,田明,王淼,等.延胡索现代药理及临床研究进展[J].中医药学报,2010,38(6):108-111.
[12] 马丙祥,董宠凯.丹参的药理作用研究新进展[J].中国药房,2014,25(7):663-665.
[13] 曹玫,张洪,张晓燕,等.香附的药理活性作用研究进展[J].药物流行病学杂志,2010,19(2):111-113.
[14] 沈晓东,黄黛瑛.白芍抗炎镇痛的药理学研究进展[J].中国现代药物应用,2009,3(24):197-199.
[15] 胡伏莲.幽门螺杆菌研究聚焦和进展[J].胃肠病学,2015, 20(12):705-707.
[16] 蔡和利,肖林榕,林栋,等.幽门螺旋杆菌感染的中药治疗近况[J].海峡药学,2014,26(7):97-100.
[17] 王春花.中药抗幽门螺旋杆菌研究进展[J].陕西中医,2011,32(6):763-765.
[18] 邓天好,谭达全,龙承星,等.半夏泻心汤治疗幽门螺杆菌相关性胃病与消化性溃疡的Meta分析[J].湖南中医杂志,2015,31(10):134-136.
[19] 沈正泽,古锐,曾宪泉,等.基于数据挖掘的中药专利复方治疗幽门螺杆菌相关性胃病的用药规律分析[J].中国中西医结合消化杂志,2016,24(8):608-611.
[20] 陈光兰,陈成龙,汪望月,等.基于聚类分析和主成分分析探讨治疗幽门螺杆菌感染的中药方剂的用药规律[J].医学研究杂志,2013,42(6):108-111. |
|
|
|