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Effect of Modified Danggui Niantong Decoction in the treatment of diabetic peripheral neuropathy |
SONG Jun TONG Xiaolin▲ |
Department of Endocrine, Guang′anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China |
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Abstract Objective To observe clinical efficacy of Modified Danggui Niantong Decoction in the treatment of diabetic peripheral neuropathy. Methods Sixty patients with diabetic peripheral neuropathy in Department of Endocrine, Guang′anmen Hospital from January 2017 to December 2018 were selected and divided into control group and treatment group according to random number table method, 30 cases in each group. In addition to basic treatment, control group was treated with Mecobalamin, and treatment group was treated with Modified Danggui Niantong Decoction for 30 days. The curative effect of two groups was compared. FPG, 2hPBG, HbA1c, TG/HDL-C, MNCV and SNCV of median nerve and common peroneal nerve of two groups were observed before and after treatment. Results Total effective rate of treatment group was higher than that of control group (P < 0.05). FPG and TG/HDL-C in treatment group after treatment were lower than those in control group (P < 0.05). FPG, 2hPBG, HbA1c and TG/HDL-C in treatment group after treatment were lower than those before treatment (P < 0.05). The 2hPBG of control group after treatment was lower than that before treatment (P < 0.05). After treatment, the median nerve MNCV, median nerve SNCV, common peroneal nerve MNCV and common peroneal nerve SNCV of two groups were faster than those before treatment (P < 0.05). Conclusion Modified Danggui Niantong Decoction can improve the nerve conduction velocity of patients with diabetic peripheral neuropathy, improve the clinical symptoms of patients, and reduce TG/HDL-C, the curative effect is significant.
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