|
|
Effect and safety of systemic lymph node dissection and sampling for early lung cancer |
QIN Dalei1 CHEN Liang2 GENG Yuliu1 LI An1 |
1.Department of Cardiothoracic Surgery, General Hospital of Wanbei Coal and Power Group, Anhui Province, Suzhou 234000, China;
2.Department of Thoracic Surgery ,Nanjing Chest Hospital, Jiangsu Province, Nanjing 210009, China |
|
|
Abstract To analyze the effect and complications of systemic lymphadenectomy for early lung cancer. Methods The data of 80 patients with early stage non-small cell lung cancer who were treated in the Department of Cardiothoracic Surgery, General Hospital of Wanbei Coal and Power Group from August 2016 to October 2019 were selected, they were divided into research group (systemic lymph node cleaning and sampling) and control group (normal operation) according to whether the systematic lymph node cleaning and sampling was, with 40 cases in each group. The clinical data of the patients were analyzed retrospectively, and the perioperative indexes and safety indexes of the two groups were compared. Results The operation time and hospitalization time of the research group were longer than those of the control group, and the differences were statistically significant (P < 0.05). There was no significant differences in incision length, intraoperative bleeding and drainage tube removal time between the two groups (P > 0.05). There was no statistically significant difference in the incidence of postoperative complications between the two groups (P > 0.05). Conclusion Systematic lymph node dissection and sampling will not increase the incidence of postoperative complications, and it is beneficial to improve the prognosis of patients, which is worthy of clinical application and promotion.
|
|
|
|
|
[1] 石远凯,孙燕,于金明,等.中国晚期原发性肺癌诊治专家共识(2016年版)[J].中国肺癌杂志,2016,19(1):1-15.
[2] Trufelli DC,Moraes TV,Lima AAP R,et al. Epidemiological profile and prognostic factors in patients with lung cancer [J]. AMB Rev Assoc Med Bras,2016,62(5):428-430.
[3] Reck M,Rabe KF. Precision Diagnosis and Treatment for Advanced Non-Small-Cell Lung Cancer [J]. N Engl J Med,2017,377(9):849-861.
[4] Shao C,Zheng C,Yan W,et al. Evaluation of efficacy and safety of minimally invasive segmentectomy in the treatment of lung cancer [J]. Oncol Lett,2018,15(6):9516-9522.
[5] Adachi H,Sakamaki K,Nishii T,et al. Lobe-Specific Lymph Node Dissection as a Standard Procedure in Surgery for Non-Small Cell Lung Cancer:A Propensity Score Matching Study [J]. J Thorac Oncol,2016,12(1):85-93.
[6] 王杰.胸腔镜下亚肺叶切除及纵隔淋巴结采样治疗早期非小细胞肺癌临床疗效探讨[J].临床肺科杂志,2016,21(1):33-36.
[7] 李刚,罗俊,邓汉宇,等.非小细胞肺癌术中淋巴结清扫方式的研究进展[J].中国胸心血管外科临床杂志,2019, 26(3):282-289.
[8] 王丽.中国原发性肺癌诊疗规范(2015年版)解读[J].中华肿瘤杂志,2015,37(1):433-436.
[9] 朱文智,季新强,谭宏宇.围术期因素对肺癌术后远期生存影响回顾性分析[J].中华肿瘤防治杂志,2017,24(19):1387-1391.
[10] 金发光.我国肺癌早期筛查现状分析[J].医学与哲学,2017,38(2):14-18.
[11] 白春学.肺癌防治策略与预测和诊断技术研究进展及展望[J].国际呼吸杂志,2019,39(9):641-648.
[12] 吕宏伟,李印,周美宏,等.肺段与肺叶切除术对早期肺癌术后肺功能影响的meta分析[J].中华胸心血管外科杂志,2017,33(9):534-538.
[13] Sun HH,Sesti J,Donington JS. Surgical Treatment of Early l Stage Lung Cancer:What has Changed and What will Change in the Future [J]. Semin Respir Crit Care Med,2016,37(5):708-715.
[14] Yang F,Sui X,Chen X,et al. Sublobar resection versus lobectomy in Surgical Treatment of Elderly Patients with early-stage non-small cell lung cancer(STEPS):study protocol for a randomized controlled trial [J]. Trials,2016, 17(1):191-193.
[15] 舒媚,吴振兴,朱振亮,等.血清肿瘤标志物联合检测在肺癌诊断中的价值[J].中华全科医学,2016,14(6):1019-1021.
[16] 胡坚,包飞潮.早期非小细胞肺癌外科治疗新进展[J].中国肺癌杂志,2016,19(6):399-402.
[17] 陈灿,鲍传明.系统性淋巴结清扫治疗肺癌附154例临床观察[J].中华肿瘤防治杂志,2016(s1):105-106.
[18] 敬涛,冯海明,马建兴,等.非小细胞肺癌淋巴结清扫方式的系统评价和Meta分析[J].中国胸心血管外科临床杂志,2018,25(8):659-669.
[19] 敬涛,杨建宝,冯海明,等.早期非小细胞肺癌不同淋巴结清扫方式疗效及安全性的Meta分析[J].中国循证医学杂志,2018,18(1):43-51.
[20] Zhong WZ,Liu SY,Wu YL. Numbers or Stations: From Systematic Sampling to Individualized Lymph Node Dissection in Non-Small-Cell Lung Cancer [J]. J Clin Oncol,2017,35(11):1143.
[21] Wang YN,Yao S,Wang CL,et al. Clinical Significance of 4L Lymph Node Dissection in Left Lung Cancer [J]. J Clin Oncol,2018,36(29):2935-2942.
[22] Wu XN,Xie MR,Xu SB,et al,Prognostic Significance of the Number of Removed Lymph Nodes in Pathologic Node-Negative Non-small Cell Lung Cancer [J]. Indian J Surg,2018,81(Suppl 7):1-7.
[23] Vial MR,O′Connell OJ,Grosu HB,et al. Diagnostic performance of endobronchial ultrasound-guided mediastinal lymph node sampling in early stage non-small cell lung cancer:A prospective study [J]. Respirology,2018, 23(1):76-81. |
|
|
|