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Effect of current perception threshold measurement on sensory quantitative evaluation of trigeminal neuralgia patients |
PAN Jie1 WEI Yujing2 XIONG Yingqiong1 WU Lingfeng1 QU Xinhui1 |
1.Department of Neurology, Jiangxi Provincial People′s Hospital People′s Hospital Affiliated to Nanchang University, Jiangxi Province, Nanchang 330006, China; 2.Department of Hematopathology, Jiangxi Provincial People′s Hospital People′s Hospital Affiliated to Nanchang University, Jiangxi Province, Nanchang 330006, China |
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Abstract Objective To evaluate the effect of current perception threshold (CPT) measurement on sensory quantification in patients with trigeminal neuralgia. Methods From January 2017 to October 2018, 26 patients with primary trigeminal neuralgia involving the mandibular branches were selected from the Inpatient Department of Neurology or Outpatient Department of Jiangxi Provincial People′s Hospital. All patients were routinely treated with nutritive nerve drugs. The CPT and the simplified McGill pain questionnaire (SF-MPQ) were measured before, 7 and 14 days after treatment, and the CPT and SF-MPQ pain score were compared to evaluate the application value of CPT in the sensory function of patients with trigeminal neuralgia before and after treatment. Results Before treatment, when stimulated by 5 and 250 Hz, CPT on the affected side was higher than that on the healthy side, with statistically significant differences (all P < 0.05); while when stimulated by 2000 Hz, CPT on both sides showed no statistically significant difference (P > 0.05). CPT at 7 and 14 days after treatment on the affected side decreased under 5 and 250 Hz stimulation compared with before treatment, and the differences were statistically significant (all P < 0.05), while CPT on the affected side at 7 and 14 days after treatment under 2000 Hz stimulation was not statistically significant compared with that before treatment (P > 0.05). The pain score of SF-MPQ at 7 and 14 days after treatment was lower than that before treatment, and the differences were statistically significant (all P < 0.05). Pearson correlation analysis showed that SF-MPQ pain score at 7 and 14 days after treatment was positively correlated with CPT under 5 Hz stimulation of the affected mandibular branches (r = 0.656, 0.418, 0.697, P < 0.05). Conclusion CPT can quantitatively detect the sensory function of patients with trigeminal neuralgia before and after treatment, and objectively evaluate the severity of the condition before and after treatment and the therapeutic effect.
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