红细胞体积分布宽度对急性失代偿射血分数保留心力衰竭患者预后的预测价值

Abstract
Figure/Table
References (23)
Related Citation (15)

Download: PDF (642 KB) HTML (1 KB)
Export: BibTeX | EndNote (RIS)

Abstract Objective To explore prognostic value of red blood cell distribution width (RDW) in patients with acute decompensated heart failure with preserved ejection fraction (HFpEF). Methods One hundred and twenty-nine patients with acute decompensated HFpEF admitted to People′s Hospital of Xuancheng City from January 2014 to December 2018 were selected. RDW level on admission was measured and followed up for 12 months. Patients were divided into good prognosis group and poor prognosis group according to the death and re-hospitalization of acute heart failure during the follow-up period. Clinical baseline of two groups was compared, and the value of RDW in predicting the prognosis of acute decompensated HFpEF patients was analyzed by receiver operating characteristic (ROC) curve. Results One hundred and twenty-one patients were followed up, 37 cases in poor prognosis and 84 cases in good prognosis. The age, the proportion of essential hypertension, the proportion of diabetes, atrial fibrillation, New York Heart Disease Association (NYHA) grade, creatinine, alanine aminotransferase, troponin I and RDW levels between two groups were compared, the differences were statistically significant (P < 0.05). Multiple logistic regression analysis showed that the history of atrial fibrillation (OR = 1.865, 95%CI: 1.325-12.592), NYHA grade (OR = 1.536, 95%CI: 1.205-10.628) and RDW (OR = 2.298, 95%CI: 1.406-16.274) were related to the poor prognosis of acute decompensated HFpEF (all P ＜ 0.01). ROC analysis results showed that RDW predicted acute decompensated HFpEF prognosis with the best cut-off value of 15%, the area under the curve was 0.724, the sensitivity was 72.97%, and the specificity was 66.67%. Conclusion The rise of RDW is closely related to the poor prognosis of acute decompensated HFpEF patients. RDW can be used as an auxiliary index to predict the prognosis of acute decompensated HFpEF patients.

Key words： Red blood cell volume distribution width Heart failure with preserved ejection fraction Prognosis Predictive value

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	GUO Qinghong1 TANG Long2 FENG Qifan2 XI Xiaotu3

Cite this article:

GUO Qinghong1 TANG Long2 FENG Qifan2 XI Xiaotu3. Prognostic value of red blood cell volume distribution width in patients with acute decompensated heart failure with preserved ejection fraction[J]. 中国医药导报, 2020, 17(23): 20-23,27.

URL:

http://www.yiyaodaobao.com.cn/EN/ OR http://www.yiyaodaobao.com.cn/EN/Y2020/V17/I23/20

[1] Fabiszak T，?覵ach P，Ratajczak J，et al. Influence of QRS duration and axis on response to cardiac resynchronization therapy in chronic heart failure with reduced left ventricular ejection fraction：a single center study including patients with left bundle branch block [J]. Cardiol J，2018. doi：10.5603/CJ.a2018.0138. [Online ahead of print].
[2] Araiza-Garaygordobil D，Fuentes-Mendoza A，Guerrero-Pando C，et al. Heart failure with preserved ejection fraction：the dark side of an old disease [J]. Arch Cardiol Mex，2019，89（4）：360-368.
[3] Yoon S，Eom GH. Heart failure with preserved ejection fraction：present status and future directions [J]. Exp Mol Med，2019，51（12）：161.
[4] Magri CJ，Tian TX，Camilleri L，et al. Red blood cell distribution width and myocardial scar burden in coronary artery disease [J]. Postgrad Med J，2017，93（1104）：607-612.
[5] Qian H，Luo Z，Xiao C，et al. Red cell distribution width in coronary heart disease：prediction of restenosis and its relationship with inflammatory markers and lipids [J]. Postgrad Med J，2018，94（1115）：489-494.
[6] 中华医学会心血管病学分会，中华心血管病杂志编辑委员会.中国心力衰竭诊断和治疗指南2014[J].中华心血管病杂志，2014，42（2）：98-122.
[7] 中华医学会心血管病学分会，中华心血管病杂志编辑委员会.急性心力衰竭诊断和治疗指南[J].中华心血管病杂志，2010，38（3）：195-207.
[8] 边长勇，尹宗宪，李涛，等.射血分数保留与射血分数降低的充血性心力衰竭患者左室结构和功能比较[J].心脏杂志，2015，27（5）：588-591.
[9] Solomon SD，McMurray JJV，Anand IS，et al. Angiotensin-neprilysin inhibition in heart failure with preserved ejection fraction [J]. N Engl J Med，2019，381（17）：1609-1620.
[10] 周军，袁慧.红细胞分布宽度在自身免疫性疾病中的研究进展[J].承德医学院学报，2018，35（4）：333-336.
[11] 李新叶，陆元奉，唐慧荷，等.红细胞分布宽度在儿童过敏性紫癜中的临床价值[J/CD].中华临床医师杂志：电子版，2019，13（1）：7-12.
[12] 杨创，陈兆生，马承恩，等.BISAP评分联合红细胞分布宽度早期评估急性胰腺炎严重程度的价值[J].中国现代普通外科进展，2018，21（4）：284-286，291.
[13] 张冬花，李志忠，张京梅，等.红细胞分布宽度与冠心病患者经皮冠状动脉介入治疗术后支架内再狭窄的相关性研究[J].中国综合临床，2017，33（12）：1084-1088.
[14] Chang XW，Zhang SY，Wang H，et al. Combined value of red blood cell distribution width and global registry of acute coronary events risk score on predicting long-term major adverse eardica events in STEMI patients undergoing primary PCI [J]. Oncotarget，2018，9（17）：13971-13980.
[15] Tureato G，Serafini V，Dilda A，et al. Red blood cell distribution width independently prediets medium-term mortality and major adverse cardiac events after an acute coronary syndrome [J]. Ann Transl Med，2016，4（13）：254.
[16] 蒋宏辉，何华，赖春进.血小板参数和红细胞参数与心肌梗死的相关性研究[J].中国医药科学，2018，8（3）：209-211，230.
[17] 李琳，刘广交.RDW与急性冠脉综合征冠脉病变严重程度及远期预后相关性的临床价值[J].中国医药科学，2020，10（4）：233-236.
[18] 王艳飞，赵春生，牛兴杰，等.红细胞分布宽度与修正休克指数对ST段抬高型心肌梗死患者Mace预后的预测价值[J].河北医学，2019，25（4）：683-687.
[19] Fang S，Zhang Z，Wang Y，et al. Predictive value of left ventricular myocardial strain by four-dimensional speckle tracking echocardiography combined with red cell distribution width in heart failure with preserved ejection fraction [J]. Echocardiography，2019，36（6）：1074-1083.
[20] Paulus WJ，Tsch?觟pe C. A novel paradigm for heart failure with preserved ejection action [J]. J Am Coll Cardiol，2013，61（4）：263-271.
[21] Imai R，Uemura Y，Okumura T，et al. Impact of red blood cell distribution width on non-cardiac mortality in patients with acute decompensated heart failure with preserved ejection fraction [J]. J Cardiol，2017，70（6）：591-597.
[22] Sotiropoulos K，Yerly P，Monney P，et al. Red cell distribution width and mortality in acute heart failure patients with preserved and reduced ejection fraction [J]. ESC Heart Fail，2016，3（3）：198-204.
[23] 陈泽芳，赖志杰，辛延国，等.射血分数保留型心力衰竭合并心房颤动的发病机制及治疗进展[J].临床内科杂志，2019，36（2）：142-144.