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Treatment of SAPHO syndrome with combination of Chinese and Western medicine: a case report |
LYU Wenli1 SHI Zhouwei2 LIN Changsong3 |
1.The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510006, China;
2.Department of Rheumatology, the First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Province, Guangzhou 510405, China |
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Abstract Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a type of rare disease involving skin, bone and joint lesions. Its skin lesions are characteristic, including palmoplantar pustular disease, pustular psoriasis, fulminant acne, acne conglobata and hidradenitis suppurativa, but skin manifestations are not necessary. Osteoarticular changes in the middle sternal rib clavicle area of bone fat thickness and bone sclerosis, that is, “tau sign” has a high degree of characteristics. Due to the characteristics of SAPHO syndrome, such as high misdiagnosis rate, long diagnosis time, and no recognized diagnosis and treatment guidelines, SAPHO syndrome has caused huge burden and trouble to patients with this disease. The diagnosis and treatment based on TCM syndrome differentiation can give patients with SAPHO syndrome a significant effect in controlling disease activity and improving quality of life. This paper reports a case of SAPHO syndrome treated with traditional Chinese and Western medicine and reviews related literature, so as to increase the understanding of SAPHO syndrome, at the same time to explore the advantages of TCM in treating this disease.
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