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| Research progress of curcumin pharmacological effect and mechanism |
| SONG Liping1 WANG Yu2 |
1.College of Basic Medicine, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China;
2.Research Center, Shaanxi University of Chinese Medicine, Shaanxi Province, Xianyang 712046, China |
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Abstract Curcumin is a plant polyphenol extracted from turmeric of traditional Chinese medicine, and it is also the most important active component of turmeric to play a pharmacological role. Modern pharmacological studies have shown that curcumin has anti-tumor, anti-inflammatory, anti-oxidation, anti-fibrosis and myocardial protection and other pharmacological effects. This paper synthesizes the literature of recent years to elaborate the anti-tumor mechanism of curcumin (including inhibiting tumor cell angiogenesis, inhibiting tumor cell proliferation, repressing cell cycle, inducing apoptosis, inhibiting tumor cell migration and invasion, etc.) and the treatment of various tumor, non-tumor diseases by curcumin by exerting its anti-inflammatory, anti-oxidation, anti-fibrotic, myocardial protection, etc., in order to provide reference for the development and utilization of curcumin.
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